LSBio
LSBio
Products
Services
Research Areas
Resources
Contact Us
Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)

How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Products
Services
Research Areas
Resources
Contact Us
PTPN6 / SHP1 Antibody (aa570‑582) LS‑C34687
SHP1 antibody LS-C34687 is an unconjugated goat polyclonal antibody to human SHP1 (PTPN6). Validated for Peptide-ELISA and WB.
Catalog
Size
Price
LS-C34687-100
100 µg (0.5 mg/ml)
Unavailable

Popular PTPN6 / SHP1 Products

Anti-PTPN6 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6262 dilution 1:200.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA
Anti-PTPN6 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6263 dilution 1:200.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA
Anti-PTPN6 antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7506 concentration 5 ug/ml.
Species: Human, Mouse, Rat, Hamster
Applications: IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Antibody
Species: Human
Applications: Western blot, ELISA
Antibody
Species: Human
Applications: Western blot, ELISA

Product Description

SHP1 antibody LS-C34687 is an unconjugated goat polyclonal antibody to human SHP1 (PTPN6). Validated for Peptide-ELISA and WB.
About PTPN6 / SHP1
PTPN6 / SHP1 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. P29350 NM_002831 NP_002822.2

PTPN6 Antibody, HCP Antibody, HPTP1C Antibody, Hematopoietic cell phosphatase Antibody, PTP-1C Antibody, SH-PTP1 Antibody, SHP-1L Antibody, SHP-1 Antibody, Shptp1 Antibody, HCPH Antibody, PTP1C Antibody, SHP1 Antibody


Specifications

Target
Human PTPN6 / SHP1
Host
Goat
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Monkey, Horse (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (0.2 - 0.5 µg/ml)
  • Peptide Enzyme-Linked Immunosorbent Assay (1:128000)
Immunogen
PTPN6 / SHP1 antibody was raised against synthetic peptide C-HTKNKREEKVKKQ from an internal region (near the C-terminus) of human PTPN6 (NP_536858.1; NP_002822.2). Percent identity by BLAST analysis: Human, Gorilla (100%); Monkey, Marmoset, Horse (92%); Rat, Hamster, Panda, Bovine, Pig (85%).
Blocking Peptide
LS-E26307 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C34687. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa570-582
Specificity
Human PTPN6. This antibody is expected to recognise both reported isoforms (NP_536858.1and NP_002822.2)
Usage
Peptide ELISA: antibody detection limit dilution 1:128000. Western blot: Approx 70 kDa band observed in lysates of cell lines Jurkat and U937 (calculated MW of 67.7 kDa according to NP_536858.1 and 67.6 kDa according to NP_002822.2). Recommended concentration: 0.2-0.5 ug/ml.
Presentation
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Storage
Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

Publications (0)


Customer Reviews (0)


Images


Western blot

PTPN6 antibody (0.2 ug/ml) staining of Jurkat cell lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
PTPN6 antibody (0.2 ug/ml) staining of Jurkat cell lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Western blot

PTPN6 antibody (0.2 ug/ml) staining of Jurkat cell lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
PTPN6 antibody (0.2 ug/ml) staining of Jurkat cell lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Western blot

PTPN6 antibody (0.2 ug/ml) staining of Jurkat cell lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
PTPN6 antibody (0.2 ug/ml) staining of Jurkat cell lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Western blot

PTPN6 antibody (0.2 ug/ml) staining of Jurkat cell lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
PTPN6 antibody (0.2 ug/ml) staining of Jurkat cell lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.


Requested From: 
Date Requested: 6/25/2018

Get Social With Us! Follow us on Facebook Follow us on Google+ Follow us on LinkedIn PSL Alliance Member
Copyright © 2018 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy



Catalog Number