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Anti-PTPN22 / PEP Antibody (aa767-781) LS-C3104

Catalog Size Price
LS-C3104-100 100 µg Unavailable

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100% Guaranteed
Rabbit Polyclonal to Human PTPN22 / PEP


Human PTPN22 / PEP
Human (tested or 100% immunogen sequence identity)
Monkey (at least 90% immunogen sequence identity)
Protein G purified


ELISA (1:1000)

Specificity and Use

PTPN22 / PEP antibody was raised against synthetic peptide from human PTPN22. Percent identity by BLAST analysis: Human, Gibbon, Marmoset (100%); Monkey (93%); Horse (87%); Elephant (80%).
KLH conjugated synthetic peptide comprising amino acids 767 - 781 [CPPNKPAESVQSNNS] of the human non-receptor type 22 protein tyrosine phosphatase (PTPN22) protein.


PBS, 0.09% sodium azide.
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
For research use only.

About PTPN22 / PEP

Q9Y2R2 NM_015967 NP_057051.3

PTPN22 Antibody, 70zpep Antibody, Lymphoid phosphatase Antibody, LYP Antibody, PEST-domain phosphatase Antibody, LYP2 Antibody, LYP1 Antibody, PEP Antibody, PTPN8 Antibody

Acts as negative regulator of T-cell receptor (TCR) signaling by direct dephosphorylation of the Src family kinases LCK and FYN, ITAMs of the TCRz/CD3 complex, as well as ZAP70, VAV, VCP and other key signaling molecules. Associates with and probably dephosphorylates CBL. Dephosphorylates LCK at its activating 'Tyr-394' residue. Dephosphorylates ZAP70 at its activating 'Tyr-493' residue. Dephosphorylates the immune system activator SKAP2.

Requested From: 
Date Requested: 5/21/2018

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