PTPN22 / PEP

protein tyrosine phosphatase, non-receptor type 22 (lymphoid)

Acts as negative regulator of T-cell receptor (TCR) signaling by direct dephosphorylation of the Src family kinases LCK and FYN, ITAMs of the TCRz/CD3 complex, as well as ZAP70, VAV, VCP and other key signaling molecules. Associates with and probably dephosphorylates CBL. Dephosphorylates LCK at its activating 'Tyr-394' residue. Dephosphorylates ZAP70 at its activating 'Tyr-493' residue. Dephosphorylates the immune system activator SKAP2.

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Products

Antibodies (39)

Proteins (6)

Type

Over-Expression Lysate (2)

Primary (39)

Recombinant (4)

Target

PTPN22 / PEP (45)

Reactivity

Human (31)

Mouse (9)

Rat (15)

Application

IHC (6)

IHC-P (2)

WB (39)

ELISA (11)

IF (1)

IP (1)

Peptide-ELISA (1)

Host

rabbit (37)

mouse (2)

Product Group

IHCPlus (1)

Isotype

IgG (12)

IgG1 (1)

IgG2a,k (1)

Clonality

monoclonal mc (2)

polyclonal pc (37)

Clone

1A6 (1)

OTI6B1 (1)

Format

APC (2)

APC Conjugated (3)

Azide-free (1)

Biotin Conjugated (4)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (3)

Unconjugated (17)

Epitope

aa663-691 (7)

aa361-410 (4)

N-Terminal (1)

aa359-449 (1)

Publications

No (45)

Tag

GST (1)

GST, N-terminus (1)

His-T7, N-terminus (2)

Myc-DDK (Flag) (2)

Species

Human (4)

Rat (1)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (2)

Select

Human PTPN22 / PEP Protein (Recombinant GST) (Full Length) - LS-G33116

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

45.43 kDa

Price:

10 µg/$479; 25 µg/$670

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PTPN22 / PEP Antibody LS-C662657

Antibody:

PTPN22 / PEP Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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IHC-plus™ PTPN22 / PEP Antibody (clone 1A6) LS-B6396

(4.0) Rating

Antibody:

PTPN22 / PEP Mouse anti-Human Monoclonal (1A6) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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PTPN22 / PEP Antibody LS-C754868

Antibody:

PTPN22 / PEP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$331

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PTPN22 / PEP Antibody (aa359-449, clone OTI6B1) LS-C795313

Antibody:

PTPN22 / PEP Mouse anti-Human Monoclonal (aa359-449) (OTI6B1) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$434

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PTPN22 / PEP Antibody LS-C800498

Antibody:

PTPN22 / PEP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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PTPN22 / PEP Antibody LS-C192963

Antibody:

PTPN22 / PEP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µl/$356; 100 µl/$461

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PTPN22 / PEP Antibody LS-C331447

Antibody:

PTPN22 / PEP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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PTPN22 / PEP Antibody (aa663-691) LS-C330040

Antibody:

PTPN22 / PEP Rabbit anti-Human Polyclonal (aa663-691) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

PTPN22 / PEP Antibody (aa663-691, Biotin) LS-C217046

Antibody:

PTPN22 / PEP Rabbit anti-Human Polyclonal (aa663-691) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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PTPN22 / PEP Antibody (aa663-691, FITC) LS-C217047

Antibody:

PTPN22 / PEP Rabbit anti-Human Polyclonal (aa663-691) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

PTPN22 / PEP Antibody (aa663-691, APC) LS-C217044

Antibody:

PTPN22 / PEP Rabbit anti-Human Polyclonal (aa663-691) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

PTPN22 / PEP Antibody (aa663-691, Azide-free, HRP) LS-C217048

Antibody:

PTPN22 / PEP Rabbit anti-Human Polyclonal (aa663-691) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

PTPN22 / PEP Antibody (aa663-691, PE) LS-C217049

Antibody:

PTPN22 / PEP Rabbit anti-Human Polyclonal (aa663-691) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

Select

PTPN22 / PEP Antibody (N-Terminal) LS-C385667

Antibody:

PTPN22 / PEP Rabbit anti-Human Polyclonal (N-Terminal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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PTPN22 / PEP Antibody LS-C824712

Antibody:

PTPN22 / PEP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

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PTPN22 / PEP Antibody LS-C769976

Antibody:

PTPN22 / PEP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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PTPN22 / PEP Antibody (aa361-410) LS-C205805

Antibody:

PTPN22 / PEP Rabbit anti-Human Polyclonal (aa361-410) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

PTPN22 / PEP Antibody (aa663-691) LS-C162305

Antibody:

PTPN22 / PEP Rabbit anti-Human Polyclonal (aa663-691) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Select

PTPN22 / PEP Antibody LS-C663345

Antibody:

PTPN22 / PEP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225

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PTPN22 / PEP Antibody (Biotin) LS-C687947

Antibody:

PTPN22 / PEP Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348

Select

PTPN22 / PEP Antibody (FITC) LS-C694857

Antibody:

PTPN22 / PEP Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$348; 200 µl/$407; 500 µl/$605; 1 ml/$755; 2 ml/$993; 5 ml/$1,716

Select

PTPN22 / PEP Antibody (PE) LS-C726645

Antibody:

PTPN22 / PEP Rabbit anti-Human Polyclonal (PE) Antibody

Reactivity:

Human

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451

• Unconjugated
• Biotin
• FITC
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • PE

Select

PTPN22 / PEP Antibody LS-C761026

Antibody:

PTPN22 / PEP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

30 µl/$255; 100 µl/$299; 200 µl/$351

Select

PTPN22 / PEP Antibody LS-C416074

Antibody:

PTPN22 / PEP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

50 µg/$305; 100 µg/$357

Viewing 1-25 of 45 product results

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