LSBio
LSBio
Products
Services
Research Areas
Resources
Contact Us
Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)

How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Products
Services
Research Areas
Resources
Contact Us
PTPN11 / SHP‑2 / NS1 Antibody (Tyr542) LS‑C34491
NS1 antibody LS-C34491 is an unconjugated rabbit polyclonal antibody to NS1 (PTPN11 / SHP-2) from human, mouse and rat. Validated for IF, IHC and WB.
Catalog
Size
Price
LS-C34491-50
50 µg (1 mg/ml)
Unavailable

Popular PTPN11 / SHP-2 / NS1 Products

Anti-PTPN11 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B542 concentration 5 ug/ml.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot
Anti-PTPN11 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1391 concentration 5 ug/ml.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot
Anti-PTPN11 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4418 concentration 3.75 ug/ml.
Species: Human, Monkey, Bat, Bovine, Horse, Rabbit, Chicken, Xenopus
Applications: IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
IHC of paraffin-embedded breast cancer tissues using PTPN11 mouse monoclonal antibody with DAB staining.
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry, ELISA
Immunohistochemical analysis of SHPTP2 (pY542) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Species: Human, Mouse, Rat, Bovine, Dog, Pig, Rabbit, Sheep, Chicken
Applications: IHC, IHC - Paraffin, Western blot

Product Description

NS1 antibody LS-C34491 is an unconjugated rabbit polyclonal antibody to NS1 (PTPN11 / SHP-2) from human, mouse and rat. Validated for IF, IHC and WB.
About PTPN11 / SHP-2 / NS1
PTPN11 / SHP-2 / NS1 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. Q06124 NM_002834 NP_002825.3

PTPN11 Antibody, Bptp-3 Antibody, BPTP3 Antibody, CFC Antibody, Csw Antibody, Corkscrew csw Antibody, Gene corkscrew Antibody, Phosphatase corkscrew Antibody, PTP-2C Antibody, SHP2 Antibody, PTP-1D Antibody, PTP2C Antibody, SHP-2 Antibody, SHPTP2 Antibody, Noonan syndrome 1 Antibody, SH-PTP2 Antibody, SH-PTP3 Antibody


Specifications

Target
Human PTPN11 / SHP-2 / NS1
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin
  • Immunofluorescence
  • Western blot
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic peptide from human PTPN11.
Epitope
Tyr542
Presentation
PBS, 0.02% sodium azide, 50% glycerol.
Storage
Short term: -20°C; Long term: -70°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

Publications (0)


Customer Reviews (0)


Images


Immunohistochemistry

Immunohistochemistry of paraffin-embedded human breast carcinoma tissue using SHP-2(Ab-542) antibody (left) or the same antibody preincubated with blocking peptide (right).
Immunohistochemistry of paraffin-embedded human breast carcinoma tissue using SHP-2(Ab-542) antibody (left) or the same antibody preincubated with blocking peptide (right).

Immunofluorescence

Immunofluorescence staining of methanol-fixed HeLa cells using SHP-2(Ab-542) antibody.
Immunofluorescence staining of methanol-fixed HeLa cells using SHP-2(Ab-542) antibody.

Western blot

Western blot of extracts from 3T3 cells using SHP-2(Ab-542) antibody.
Western blot of extracts from 3T3 cells using SHP-2(Ab-542) antibody.

Immunohistochemistry

Immunohistochemistry of paraffin-embedded human breast carcinoma tissue using SHP-2(Ab-542) antibody (left) or the same antibody preincubated with blocking peptide (right).
Immunohistochemistry of paraffin-embedded human breast carcinoma tissue using SHP-2(Ab-542) antibody (left) or the same antibody preincubated with blocking peptide (right).

Immunofluorescence

Immunofluorescence staining of methanol-fixed HeLa cells using SHP-2(Ab-542) antibody.
Immunofluorescence staining of methanol-fixed HeLa cells using SHP-2(Ab-542) antibody.

Western blot

Western blot of extracts from 3T3 cells using SHP-2(Ab-542) antibody.
Western blot of extracts from 3T3 cells using SHP-2(Ab-542) antibody.

Immunohistochemistry

Immunohistochemistry of paraffin-embedded human breast carcinoma tissue using SHP-2(Ab-542) antibody (left) or the same antibody preincubated with blocking peptide (right).
Immunohistochemistry of paraffin-embedded human breast carcinoma tissue using SHP-2(Ab-542) antibody (left) or the same antibody preincubated with blocking peptide (right).

Immunofluorescence

Immunofluorescence staining of methanol-fixed HeLa cells using SHP-2(Ab-542) antibody.
Immunofluorescence staining of methanol-fixed HeLa cells using SHP-2(Ab-542) antibody.

Western blot

Western blot of extracts from 3T3 cells using SHP-2(Ab-542) antibody.
Western blot of extracts from 3T3 cells using SHP-2(Ab-542) antibody.

Immunohistochemistry

Immunohistochemistry of paraffin-embedded human breast carcinoma tissue using SHP-2(Ab-542) antibody (left) or the same antibody preincubated with blocking peptide (right).
Immunohistochemistry of paraffin-embedded human breast carcinoma tissue using SHP-2(Ab-542) antibody (left) or the same antibody preincubated with blocking peptide (right).

Immunofluorescence

Immunofluorescence staining of methanol-fixed HeLa cells using SHP-2(Ab-542) antibody.
Immunofluorescence staining of methanol-fixed HeLa cells using SHP-2(Ab-542) antibody.

Western blot

Western blot of extracts from 3T3 cells using SHP-2(Ab-542) antibody.
Western blot of extracts from 3T3 cells using SHP-2(Ab-542) antibody.


Requested From: 
Date Requested: 6/20/2018

Get Social With Us! Follow us on Facebook Follow us on Google+ Follow us on LinkedIn PSL Alliance Member
Copyright © 2018 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy



Catalog Number