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PTP4A2 / PRL-2

protein tyrosine phosphatase type IVA, member 2

PTP4A2 / PRL-2 belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17.

Gene Name: protein tyrosine phosphatase type IVA, member 2
Family/Subfamily: Protein Phosphatase , PTP4A
Synonyms: PTP4A2, HH7-2, HH13, HU-PP-1, PRL-2, PRL2, Ptp-IV1a, PTPCAAX2, PTP(CAAXII), Ptp-IV1b, OV-1, PTP4A
Target Sequences: NM_080391 AAH70182.1 Q12974

☰ Filters
Antibodies (24)
Proteins (10)
Over-Expression Lysate (2)
Primary (24)
Recombinant (8)
PTP4A2 / PRL-2 (34)
Human (24)
Mouse (6)
Rat (6)
IHC (7)
IHC-P (4)
WB (18)
Flo (1)
ELISA (6)
IF (2)
Peptide-ELISA (1)
rabbit (22)
mouse (2)
IgG (10)
IgG1,k (1)
IgG2b (1)
monoclonal mc (2)
polyclonal pc (22)
3C2 (1)
5B6F4 (1)
APC (1)
APC Conjugated (1)
Biotin Conjugated (2)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (14)
aa32-59 (1)
aa40-69 (1)
aa58-162 (1)
No (34)
6His, C-terminus (2)
GST (2)
GST, N-terminus (1)
His (1)
His-T7, N-terminus (1)
Myc-DDK (Flag) (3)
Human (9)
293T Cells (1)
E. coli (5)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (4)
Low endotoxin level (2)
PTP4A2 / PRL-2 Antibody - Formalin-fixed and paraffin-embedded human prostate carcinoma with PTP4A2 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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PTP4A2 / PRL-2 Rabbit anti-Human Polyclonal (aa32-59) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
PTP4A2 / PRL-2 Antibody - PTP4A2 antibody IHC-paraffin. IHC(P): Human Prostatic Cancer Tissue.
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PTP4A2 / PRL-2 Rabbit anti-Human Polyclonal (aa40-69) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
PTP4A2 / PRL-2 Antibody - Immunohistochemistry image at a dilution of 1:200 and staining in paraffin-embedded human appendix tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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PTP4A2 / PRL-2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
Select
PTP4A2 / PRL-2 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
PTP4A2 / PRL-2 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
PTP4A2 / PRL-2 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
FITC Conjugated
50 µg/$294; 100 µg/$360
PTP4A2 / PRL-2 Antibody - Immunohistochemistry of paraffin-embedded Human breast cancer using PTP4A2 Polyclonal Antibody at dilution of 1:30.
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PTP4A2 / PRL-2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
PTP4A2 / PRL-2 Antibody - Western blot using PTP4A2 monoclonal antibody against human PTP4A2 recombinant protein. (Expected MW is 37.5 kDa)
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PTP4A2 / PRL-2 Mouse anti-Human Monoclonal (aa58-162) (5B6F4) Antibody
Human
ELISA, WB
Unconjugated
100 µl/$459
PTP4A2 / PRL-2 Antibody
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PTP4A2 / PRL-2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µg/$575
PTP4A2 / PRL-2 Antibody - 1:100 staining human prostate tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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PTP4A2 / PRL-2 Rabbit anti-Human Polyclonal Antibody
Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
PTP4A2 / PRL-2 Antibody
Select
PTP4A2 / PRL-2 Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
100 µl/$332
Select
PTP4A2 / PRL-2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
PTP4A2 / PRL-2 Antibody - Detection limit for recombinant GST tagged PTP4A2 is 0.03 ng/ml as a capture antibody.
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PTP4A2 / PRL-2 Mouse anti-Human Monoclonal (3C2) Antibody
Human
ELISA
Unconjugated
100 µg/$423
Select
PTP4A2 / PRL-2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
Select
PTP4A2 / PRL-2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
PTP4A2 / PRL-2 Antibody - Western Blot; Sample: Recombinant protein.
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PTP4A2 / PRL-2 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
PTP4A2 / PRL-2 Antibody - Western Blot; Sample: Recombinant protein.
Select
PTP4A2 / PRL-2 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$338; 200 µl/$393; 500 µl/$575; 1 ml/$702; 2 ml/$939; 5 ml/$1,593
PTP4A2 / PRL-2 Antibody - Western Blot; Sample: Recombinant protein.
Select
PTP4A2 / PRL-2 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348
PTP4A2 / PRL-2 Antibody - Western Blot; Sample: Recombinant protein.
Select
PTP4A2 / PRL-2 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$348; 200 µl/$407; 500 µl/$605; 1 ml/$755; 2 ml/$993; 5 ml/$1,716
PTP4A2 / PRL-2 Antibody - Western Blot; Sample: Recombinant protein.
Select
PTP4A2 / PRL-2 Rabbit anti-Human Polyclonal (APC, Cy7) Antibody
Human
WB
APC, Cy7 Conjugated
100 µl/$505; 200 µl/$648; 500 µl/$1,152; 1 ml/$1,401; 2 ml/$1,961; 5 ml/$3,676
PTP4A2 / PRL-2 Antibody - Western Blot; Sample: Recombinant protein.
Select
PTP4A2 / PRL-2 Rabbit anti-Human Polyclonal (PE) Antibody
Human
WB
PE Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
PTP4A2 / PRL-2 Antibody - Western Blot; Sample: Recombinant protein.
Select
PTP4A2 / PRL-2 Rabbit anti-Human Polyclonal (APC) Antibody
Human
WB
APC Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
PTP4A2 / PRL-2 Antibody - Western Blot; Sample: Recombinant protein.
Select
PTP4A2 / PRL-2 Rabbit anti-Human Polyclonal (Cy3) Antibody
Human
WB
Cy3 Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
PTP4A2 / PRL-2 Antibody - Western blot analysis of extracts of various cell lines, using PTP4A2 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 30s.
Select
PTP4A2 / PRL-2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
PTP4A2 / PRL-2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
18.9 kDa
20 µg/$150
Viewing 1-25 of 34 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).