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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PTK2B / PYK2 Antibody (phospho‑Tyr402) LS‑C17524
PYK2 antibody LS-C17524 is an unconjugated mouse monoclonal antibody to PYK2 (PTK2B) from human, mouse and rat. Validated for ELISA and WB.
Antibody
Catalog
Size
Price
LS-C17524-100
100 µg
$800

Popular PTK2B / PYK2 Products

Anti-PTK2B / PYK2 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4093 dilution 1:100.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA
Anti-PTK2B / PYK2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1892 dilution 1:50.
Species: Mouse, Human
Applications: IHC, IHC - Paraffin, Western blot
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using PYK2 Antibody. The picture on the right is blocked with the synthesized peptide.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Anti-PTK2B / PYK2 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7507 dilution 1:50.
Species: Rat, Human
Applications: IHC, IHC - Paraffin, Western blot, Immunoprecipitation, ELISA
Western blot of lysates from mouse brain, mouse spleen, rat brain tissue (from left to right) with Ptk2b Antibody (P769). Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20 ug per lane.
Species: Mouse, Rat
Applications: Western blot

Product Description

PYK2 antibody LS-C17524 is an unconjugated mouse monoclonal antibody to PYK2 (PTK2B) from human, mouse and rat. Validated for ELISA and WB.
About PTK2B / PYK2
Non-receptor protein-tyrosine kinase that regulates reorganization of the actin cytoskeleton, cell polarization, cell migration, adhesion, spreading and bone remodeling. Plays a role in the regulation of the humoral immune response, and is required for normal levels of marginal B-cells in the spleen and normal migration of splenic B-cells. Required for normal macrophage polarization and migration towards sites of inflammation. Q14289 NM_004103 NP_004094.3

PTK2B Antibody, CADTK Antibody, CAKB Antibody, Cell adhesion kinase beta Antibody, FADK 2 Antibody, FADK2 Antibody, Focal adhesion kinase 2 Antibody, FRNK Antibody, FAK2 Antibody, Proline-rich tyrosine kinase 2 Antibody, Protein-tyrosine kinase 2-beta Antibody, Protein kinase B Antibody, Protein tyrosine kinase 2 beta Antibody, PYK2 Antibody, RAFTK Antibody, CAK-beta Antibody, PKB Antibody, PTK Antibody


Specifications

Target
Human PTK2B / PYK2
Host
Mouse
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Conjugations
Unconjugated
Purification
Gel filtration
Modifications
Unmodified
Applications
  • Western blot (0.5 µg/ml)
  • ELISA (0.05 µg/ml)
Immunogen
PTK2B / PYK2 antibody was raised against synthetic peptide corresponding to a portion of human Pyk2 (proline-rich tyrosine kinase 2) phosphorylated at Tyr402. Conjugated to KLH. Molecular Weight: 116kD.
Epitope
pTyr402
Specificity
Recognizes human Pyk2 phosphorylated at Tyr402. Species cross-reactivity: Mouse, Rat. Does not cross-react with the non-phosphorylated form of Pyk2/CAKb or with unrelated phosphorylation sites.
Usage
Suitable for use in ELISA and Western Blot. Western Blot: 0.5 ug/ml (ECL). Recommended blocking buffer: Casein/Tween 20 based blocking and blot incubation buffer. ELISA: 0.05 ug/ml.
Presentation
PBS, 0.09% Sodium Azide, 40% Glycerol, Sucrose
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: United States
Date Requested: 8/20/2018

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