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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PTK2B / PYK2 Antibody (phospho‑Tyr402) LS‑C17523
PYK2 antibody LS-C17523 is an unconjugated mouse monoclonal antibody to PYK2 (PTK2B) from human and rat. Validated for ELISA, IP and WB.
Antibody
Catalog
Size
Price
LS-C17523-200
200 µg
$680

Popular PTK2B / PYK2 Products

Anti-PTK2B / PYK2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1892 dilution 1:50.
Species: Mouse, Human
Applications: IHC, IHC - Paraffin, Western blot
Anti-PTK2B / PYK2 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4093 dilution 1:100.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using PYK2 Antibody. The picture on the right is blocked with the synthesized peptide.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Anti-PTK2B / PYK2 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7507 dilution 1:50.
Species: Rat, Human
Applications: IHC, IHC - Paraffin, Western blot, Immunoprecipitation, ELISA
Western blot of lysates from mouse brain, mouse spleen, rat brain tissue (from left to right) with Ptk2b Antibody (P769). Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20 ug per lane.
Species: Mouse, Rat
Applications: Western blot

Product Description

PYK2 antibody LS-C17523 is an unconjugated mouse monoclonal antibody to PYK2 (PTK2B) from human and rat. Validated for ELISA, IP and WB.
About PTK2B / PYK2
Non-receptor protein-tyrosine kinase that regulates reorganization of the actin cytoskeleton, cell polarization, cell migration, adhesion, spreading and bone remodeling. Plays a role in the regulation of the humoral immune response, and is required for normal levels of marginal B-cells in the spleen and normal migration of splenic B-cells. Required for normal macrophage polarization and migration towards sites of inflammation. Q14289 NM_004103 NP_004094.3

PTK2B Antibody, CADTK Antibody, CAKB Antibody, Cell adhesion kinase beta Antibody, FADK 2 Antibody, FADK2 Antibody, Focal adhesion kinase 2 Antibody, FRNK Antibody, FAK2 Antibody, Proline-rich tyrosine kinase 2 Antibody, Protein-tyrosine kinase 2-beta Antibody, Protein kinase B Antibody, Protein tyrosine kinase 2 beta Antibody, PYK2 Antibody, RAFTK Antibody, CAK-beta Antibody, PKB Antibody, PTK Antibody


Specifications

Target
Human PTK2B / PYK2
Host
Mouse
Reactivity
Human, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG1,k Monoclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Protein G purified
Modifications
Unmodified
Applications
  • Western blot
  • Immunoprecipitation (1 µg/ml)
  • ELISA
  • (applications tested for the base form of this product only)
Immunogen
PTK2B / PYK2 antibody was raised against synthetic peptide (KLH) containing. DI[pY]AE. in which pY corresponds to phosphotyrosine 402 of human Pyk2 (protein tyrosine kinase 2). The immunizing sequence is identical in human and rat.
Epitope
pTyr402
Specificity
Recognizes human phosphorylated Pyk2, MW: 116kD. Species cross-reactivity: Rat.
Usage
Suitable for use in ELISA and Immunoprecipitation/Western Blot. Not suitable for Western Blot (cross-reacts with phosphorylated FAK). Immunoprecipitation: 1 ug/ml detects phosphorylated Pyk2 in Pyk2 immunoprecipitate from RIPA lysates of PC12 cells treated with EGF, Bradykinin or KCl but not from untreated cell lysates.
Presentation
0.1 M Tris-Glycine, pH 7.4, 0.15 M NaCl, 0.05% Sodium Azide, 30% Glycerol
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: United States
Date Requested: 8/17/2018

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