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Anti-PTK2B / PYK2 Antibody (aa546-595) LS-C117576

Catalog	Size	Price
LS-C117576-50	50 µl	Unavailable
LS-C117576-100	100 µl	Unavailable

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Details

Target:	Human PTK2B / PYK2
Host:	Rabbit
Reactivity:	Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality:	IgG Polyclonal
Conjugations:	Unconjugated
Purification:	Immunoaffinity purified
Modifications:	Unmodified

Applications

Approved:

IHC (1:50 - 1:100)
Western blot (1:500 - 1:1000)
ELISA (1:10000)

Failed:

IHC - Paraffin

Specificity and Use

Immunogen:	PTK2B / PYK2 antibody was raised against synthetic peptide from human PYK2 (aa546-595).
Epitope:	aa546-595
Specificity:	PYK2 (Ab-580) Antibody detects endogenous levels of total PYK2 protein.

Packaging

Presentation:	PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Storage:	Store at -20°C for up to one year.
Restrictions:	For research use only.

About PTK2B / PYK2

Uniprot: Q14289 NCBI: NM_004103 NP_004094.3

Synonyms: PTK2B Antibody, CADTK Antibody, CAKB Antibody, Cell adhesion kinase beta Antibody, FADK 2 Antibody, FADK2 Antibody, Focal adhesion kinase 2 Antibody, FRNK Antibody, FAK2 Antibody, Proline-rich tyrosine kinase 2 Antibody, Protein-tyrosine kinase 2-beta Antibody, Protein kinase B Antibody, Protein tyrosine kinase 2 beta Antibody, PYK2 Antibody, RAFTK Antibody, CAK-beta Antibody, PKB Antibody, PTK Antibody

Description: Non-receptor protein-tyrosine kinase that regulates reorganization of the actin cytoskeleton, cell polarization, cell migration, adhesion, spreading and bone remodeling. Plays a role in the regulation of the humoral immune response, and is required for normal levels of marginal B-cells in the spleen and normal migration of splenic B-cells. Required for normal macrophage polarization and migration towards sites of inflammation.

(More About PTK2B / PYK2)

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Technical Help Review

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Western blot

Western blot of extracts from COS cells, treated with UV 15', using PYK2 (Ab-580) Antibody. The lane on the right is treated with the synthesized peptide.

Requested From:
Date Requested: 8/17/2017

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