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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PTGS2 / COX2 / COX‑2 Antibody (C‑Terminus) LS‑C79822
Antibody
COX-2 antibody LS-C79822 is an unconjugated rabbit polyclonal antibody to COX-2 (PTGS2 / COX2) from human, mouse and rat. Validated for IHC, IP and WB.
Catalog
Size
Price
LS-C79822-500
500 µl
Unavailable

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Product Description

COX-2 antibody LS-C79822 is an unconjugated rabbit polyclonal antibody to COX-2 (PTGS2 / COX2) from human, mouse and rat. Validated for IHC, IP and WB.
About PTGS2 / COX2 / COX-2
Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. P35354 NM_000963 NP_000954.1

PTGS2 Antibody, COX-2 Antibody, Cyclooxygenase-2 Antibody, COX2 Antibody, Cyclooxygenase 2b Antibody, HCox-2 Antibody, GRIPGHS Antibody, PGH synthase 2 Antibody, PGHS-2 Antibody, PHS II Antibody, PHS-2 Antibody, Prostaglandin H2 synthase 2 Antibody, PGG/HS Antibody, Prostaglandin G/H synthase 2 Antibody


Specifications

Target
Rat PTGS2 / COX2 / COX-2
Host
Rabbit
Reactivity
Rat, Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin
  • IHC - Frozen
  • Western blot
  • Immunoprecipitation
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Recombinant protein corresponding to the C-terminus of rat COX2 (the exact amino acid sequence is considered to be proprietary information).
Epitope
C-Terminus
Specificity
This antibody reacts with the 70kD protein. Species cross-reactivity: Cross-reacts with Human, Mouse and Rat.
Usage
Suitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry (Fr) (paraffin-embedded sections). Positive control: Lung carcinoma and colon carcinoma.
Presentation
PBS, pH 7.4, BSA, 10 mM sodium azide.
Storage
Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles. Store undiluted.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/19/2018

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