Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
Western blot (1 - 10 µg/ml)
ELISA (0.5 - 1 µg/ml)
Specificity and Use
PTGER2 / EP2 antibody was raised against a 14aa peptide within the 1st extracellular, N-terminal domain of human EP2 (KLH).
Recognizes human EP2 Receptor. No appreciable sequence homology with EP1, EP3, EP4, or other GPCRs. Species sequence homology: rabbit 85% and canine 71%. The sequence is not conserved in other species.
Suitable for use in ELISA and Western Blot.
PBS, pH 7.5, 0.1% BSA, 40% glycerol.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
Prostaglandin E Receptor EP2 is a member of the Prostanoid Receptor subfamily. Along with several other receptor subtypes (EP1, EP3, and EP4), it mediates the diverse biological effects of Prostaglandin E2 (PGE2). PGE2 has been implicated in numerous processes, including immune response modulation, male erectile function, induction of labor, cervical cancer, control of blood pressure, asthma, and more recently, Alzheimer's Disease.