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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PTCH1 / Patched 1 Antibody (Ala2) LS‑C176173
Patched 1 antibody LS-C176173 is an unconjugated rabbit polyclonal antibody to Patched 1 (PTCH1) from human and mouse. Validated for IHC and WB.
Catalog
Size
Price
LS-C176173-100
100 µl
Unavailable

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Product Description

Patched 1 antibody LS-C176173 is an unconjugated rabbit polyclonal antibody to Patched 1 (PTCH1) from human and mouse. Validated for IHC and WB.
About PTCH1 / Patched 1
PTCH1 / Patched 1 is a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Q13635 NM_000264 NP_000255.2

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Specifications

Target
Human PTCH1 / Patched 1
Host
Rabbit
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin
  • Western blot
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic peptide around Ala2 of human PTCH1 / Patched
Epitope
Ala2
Specificity
Human PTCH1 / Patched
Presentation
PBS, pH 7.2, 0.05% sodium azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

IHC of Patched (A2) pAb in paraffin-embedded human brain tissue.
IHC of Patched (A2) pAb in paraffin-embedded human brain tissue.

Western blot

Western blot of Patched (A2) pAb in extracts from mouse muscle cells.
Western blot of Patched (A2) pAb in extracts from mouse muscle cells.

Immunohistochemistry

IHC of Patched (A2) pAb in paraffin-embedded human brain tissue.
IHC of Patched (A2) pAb in paraffin-embedded human brain tissue.

Western blot

Western blot of Patched (A2) pAb in extracts from mouse muscle cells.
Western blot of Patched (A2) pAb in extracts from mouse muscle cells.

Immunohistochemistry

IHC of Patched (A2) pAb in paraffin-embedded human brain tissue.
IHC of Patched (A2) pAb in paraffin-embedded human brain tissue.

Western blot

Western blot of Patched (A2) pAb in extracts from mouse muscle cells.
Western blot of Patched (A2) pAb in extracts from mouse muscle cells.

Immunohistochemistry

IHC of Patched (A2) pAb in paraffin-embedded human brain tissue.
IHC of Patched (A2) pAb in paraffin-embedded human brain tissue.

Western blot

Western blot of Patched (A2) pAb in extracts from mouse muscle cells.
Western blot of Patched (A2) pAb in extracts from mouse muscle cells.


Requested From: 
Date Requested: 6/20/2018

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