Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(applications tested for the base form of this product only)
Specificity and Use
Synthetic peptide located between aa58-107 of human PTCH1 (Q6TKP8). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Dog, Bovine, Horse, Guinea pig (100%); Elephant, Bat, Rabbit, Opossum (92%); Zebra finch (85%).
LS-E16254 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-B5778. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Lyophilized from PBS with 2% sucrose
50 µl Distilled water
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
PTCH1 Antibody, NBCCS Antibody, Patched 1 Antibody, Patched homolog 1 Antibody, Protein patched homolog 1 Antibody, PTC1 Antibody, PTCH Antibody, PTCH protein +12b Antibody, PTCH protein -10 Antibody, PTCH protein -3,4,5 Antibody, Patched Antibody, Patched protein homolog 1 Antibody, BCNS Antibody, HPE7 Antibody, Patched homolog Antibody, PTC Antibody, PTCH protein +4 Antibody, PTCH11 Antibody
PTCH1 / Patched 1 is a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor.
Anti-PTCH1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5778 concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
PTCH1 antibody LS-B5778 Western blot of Jurkat lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.