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PSME2

proteasome (prosome, macropain) activator subunit 2 (PA28 beta)

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the beta subunit of the 11S regulator, one of the two 11S subunits that is induced by gamma-interferon. Three beta and three alpha subunits combine to form a heterohexameric ring. Six pseudogenes have been identified on chromosomes 4, 5, 8, 10 and 13.

Gene Name: proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
Synonyms: PSME2, REGbeta, PA28B, Proteasome activator 28-beta, MCP activator, 31-kD subunit, PA28beta, REG-beta
Target Sequences: NM_002818 NP_002809.2 Q9UL46

☰ Filters
Antibodies (37)
Proteins (7)
Over-Expression Lysate (2)
Primary (37)
Recombinant (5)
PSME2 (44)
Human (37)
Mouse (22)
Rat (9)
Bat (7)
Bovine (4)
Chimpanzee (6)
Dog (6)
Gibbon (6)
Guinea pig (3)
Hamster (7)
Horse (4)
Monkey (7)
Pig (7)
Rabbit (3)
Zebrafish (6)
IHC (20)
IHC-P (5)
WB (36)
Flo (7)
ELISA (18)
IP (3)
Peptide-ELISA (2)
rabbit (34)
mouse (2)
goat (1)
Product Group
IHCPlus (1)
IgG (20)
IgG2a,k (1)
monoclonal mc (2)
polyclonal pc (35)
1G4 (1)
APC Conjugated (1)
Biotin Conjugated (5)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (1)
Unconjugated (20)
aa61-91 (7)
C-Terminus (4)
aa143-192 (4)
aa210-239 (1)
aa223-236 (1)
No (44)
GST (2)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (3)
Human (6)
293T Cells (1)
E. coli (2)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
PSME2 Antibody - Immunoperoxidase of monoclonal antibody to PSME2 on formalin-fixed paraffin-embedded human stomach carcinoma. [antibody concentration 6 ug/ml].
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PSME2 Mouse anti-Human Monoclonal (1G4) Antibody
Human
ELISA, IHC, IHC-P, IP, WB
Unconjugated
100 µg/$423
PSME2 Antibody - Formalin-fixed and paraffin-embedded mouse hepatocarcinoma reacted with PSME2 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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PSME2 Rabbit anti-Human Polyclonal (aa61-91) Antibody
Mouse, Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
PSME2 Antibody - Anti-PSME2 antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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PSME2 Goat anti-Human Polyclonal (aa223-236) Antibody
Mouse, Bovine, Rat, Hamster, Pig, Horse, Bat, Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
Select
PSME2 Rabbit anti-Human Polyclonal (aa61-91) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
Unconjugated
200 µl/$734
Select
PSME2 Rabbit anti-Human Polyclonal (aa61-91) (HRP) Antibody
Mouse, Human
ELISA, IHC, WB
HRP Conjugated
200 µl/$952
Select
PSME2 Rabbit anti-Human Polyclonal (aa61-91) (Biotin) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200 µl/$952
Select
PSME2 Rabbit anti-Human Polyclonal (aa61-91) (FITC) Antibody
Mouse, Human
Flo, IHC, WB
FITC Conjugated
200 µl/$952
Select
PSME2 Rabbit anti-Human Polyclonal (aa61-91) (PE) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
PE Conjugated
200 µl/$952
Select
PSME2 Rabbit anti-Human Polyclonal (aa61-91) (APC) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
APC Conjugated
200 µl/$952
PSME2 Antibody - Formalin-fixed and paraffin-embedded mouse hepatocarcinoma reacted with PSME2 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Select
PSME2 Rabbit anti-Human Polyclonal (aa210-239) Antibody
Mouse, Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
Select
PSME2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
Select
PSME2 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IP, WB
Unconjugated
100 µl/$412
PSME2 Antibody - Immunohistochemical analysis of PA28 beta staining in human gastric cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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PSME2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
PSME2 Antibody - 1:100 staining rat heart tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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PSME2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
PSME2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
Select
PSME2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
60 µl/$343; 120 µl/$427; 200 µl/$559
Select
PSME2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IP, WB
Unconjugated
100 µl/$412
PSME2 Antibody - Immunohistochemistry of paraffin-embedded human gastric cancer tissue.
Select
PSME2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$287; 50 µl/$341; 100 µl/$431; 200 µl/$539
PSME2 Antibody - Immunohistochemistry of paraffin-embedded human gastric cancer using PSME2 antibody at dilution of 1:100 (40x lens).
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PSME2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
20 µl/$287; 50 µl/$341; 100 µl/$431; 200 µl/$539
Select
PSME2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
Select
PSME2 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
PSME2 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
PSME2 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
Select
PSME2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$582
Select
PSME2 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
100 µg/$582
Viewing 1-25 of 44 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).