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PSMC6

proteasome (prosome, macropain) 26S subunit, ATPase, 6

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. Pseudogenes have been identified on chromosomes 8 and 12.

Gene Name: proteasome (prosome, macropain) 26S subunit, ATPase, 6
Family/Subfamily: ATPase , not assigned-ATPase
Synonyms: PSMC6, CADP44, p42, p44, Proteasome subunit p42, SUG2
Target Sequences: NM_002806 NP_002797.3 P62333

☰ Filters
Antibodies (34)
Proteins (10)
Over-Expression Lysate (4)
Primary (34)
Recombinant (6)
PSMC6 (44)
Human (34)
Mouse (18)
Rat (10)
Bat (3)
Bovine (4)
Chicken (3)
Chimpanzee (3)
Dog (3)
Gibbon (3)
Guinea pig (3)
Horse (3)
Monkey (3)
Pig (3)
Rabbit (3)
Xenopus (3)
Zebrafish (4)
IHC (8)
IHC-P (1)
WB (29)
ELISA (8)
ICC (3)
IF (3)
IP (3)
Peptide-ELISA (3)
RNAi (1)
rabbit (32)
mouse (2)
IgG (16)
IgG2a (1)
IgG2a,k (1)
monoclonal mc (2)
polyclonal pc (32)
2C4 (1)
p42-23 (1)
APC (1)
APC Conjugated (1)
Biotin Conjugated (3)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (21)
aa2-403 (8)
C-Terminus (4)
30-110 aa, Internal (1)
Internal (1)
aa1-301 (1)
aa107-152 (1)
aa275-325 (1)
aa339-389 (1)
aa48-97 (1)
aa61-110 (1)
No (44)
GST (2)
GST, N-terminus (1)
His, N-Terminal (1)
His-T7 (1)
Myc-DDK (Flag) (5)
Human (8)
293T Cells (2)
E. coli (2)
HEK 293 Cells (3)
Wheat Germ Extract (3)
Purified (2)
PSMC6 Antibody - Immunofluorescence of monoclonal antibody to PSMC6 on HeLa cell. [antibody concentration 10 ug/ml]
Select
PSMC6 Mouse anti-Human Monoclonal (2C4) Antibody
Mouse, Rat, Human
ELISA, IF, RNAi, WB
Unconjugated
100 µg/$423
PSMC6 Antibody - IHC of paraffin-embedded HeLa xenograft using PSMC6 antibody at 1:500 dilution.
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PSMC6 Rabbit anti-Human Polyclonal (aa1-301) Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µl/$450
PSMC6 Antibody - 1:100 staining mouse liver tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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PSMC6 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
PSMC6 Antibody - Immunofluorescence staining of PSMC6 in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-human PSMC6 polyclonal antibody (dilution ratio 1:500) at 4°C overnight. Then cells were stained with the Alexa Fluor 488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to cytoplasm and nucleus.
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PSMC6 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, WB
Unconjugated
100 µl/$412
Select
PSMC6 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
Select
PSMC6 Rabbit anti-Human Polyclonal (aa339-389) Antibody
Mouse, Human
IHC, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
Select
PSMC6 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
Select
PSMC6 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
Select
PSMC6 Rabbit anti-Human Polyclonal (aa107-152) Antibody
Mouse, Rat, Human
ICC, WB
Unconjugated
50 µl/$321; 100 µl/$403
PSMC6 Antibody - Immunohistochemistry of paraffin-embedded human kidney tissue.
Select
PSMC6 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
Select
PSMC6 Rabbit anti-Human Polyclonal (aa275-325) Antibody
Human
IHC, IP
Unconjugated
10 µg/$295; 100 µl/$514
PSMC6 Antibody - Western blot of PSMC6 antibody
Select
PSMC6 Rabbit anti-Human Polyclonal (30-110 aa, Internal) Antibody
Mouse, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PSMC6 Antibody - Western blot analysis of extracts from RAW264.7 cells, 293 cells and HepG2 cells, using PSMC6 antibody.
Select
PSMC6 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
PSMC6 Antibody - Western blot analysis of lysates from HepG2, 293, and RAW264.7 cells, using PSMC6 Antibody. The lane on the right is blocked with the synthesized peptide.
Select
PSMC6 Rabbit anti-Human Polyclonal (aa61-110) Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
PSMC6 Antibody - Western blot analysis of the lysates from HeLa cells using PSMC6 antibody.
Select
PSMC6 Rabbit anti-Human Polyclonal (aa48-97) Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
PSMC6 Antibody - Western blot analysis of PSMC6 expression in HEK293 (A); HeLa (B); RAW264.7 (C) whole cell lysates.
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PSMC6 Rabbit anti-Human Polyclonal (Internal) Antibody
Zebrafish, Rat, Mouse, Bovine, Human
IP, WB
Unconjugated
100 µl/$299
PSMC6 Antibody - IHC image of PSMC6 Antibody diluted at 1:1200 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Select
PSMC6 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
50 µg/$294; 100 µg/$360
Select
PSMC6 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
PSMC6 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
PSMC6 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
PSMC6 Antibody - Western blot: Composite luminograph of (a) HeLa S3 cytosolic preparation, (b) purified 26S proteasome, and (c) human placental proteasome fraction after SDS PAGE followed by blotting onto PVDF membrane and probing with antibody BML-PW8830. Antibody dilution 1:5000 using ECL procedure (1 min exposure).
Select
PSMC6 Mouse anti-Human Monoclonal (p42-23) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$571
Select
PSMC6 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
100 µl/$386
PSMC6 Antibody - PSMC6 antibody Western blot of Jurkat lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
PSMC6 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$424
PSMC6 Antibody - Western blot of recombinant PSMC6 / p44.
Select
PSMC6 Rabbit anti-Human Polyclonal (aa2-403) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
PSMC6 Antibody - Western blot of recombinant PSMC6 / p44.
Select
PSMC6 Rabbit anti-Human Polyclonal (aa2-403) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$338; 200 µl/$393; 500 µl/$575; 1 ml/$702; 2 ml/$939; 5 ml/$1,593
Viewing 1-25 of 44 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).