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PSMC4

proteasome (prosome, macropain) 26S subunit, ATPase, 4

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the triple-A family of ATPases that is a component of the 19S regulatory subunit and plays a role in 26S proteasome assembly. The encoded protein interacts with gankyrin, a liver oncoprotein, and may also play a role in Parkinson's disease through interactions with synphilin-1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene Name: proteasome (prosome, macropain) 26S subunit, ATPase, 4
Family/Subfamily: Protease Regulatory , not assigned-Protease Regulatory
Synonyms: PSMC4, MB67-interacting protein, MIP224, RPT3, S6, Tat-binding protein 7, Protease 26S subunit 6, TBP-7, TBP7
Target Sequences: NM_006503 NP_006494.1 P43686

☰ Filters
Antibodies (31)
Proteins (7)
Over-Expression Lysate (4)
Primary (31)
Recombinant (3)
PSMC4 (38)
Human (31)
Mouse (8)
Rat (17)
Bat (3)
Bovine (6)
Chimpanzee (6)
Dog (6)
Gibbon (6)
Guinea pig (3)
Horse (3)
Monkey (6)
Pig (8)
Rabbit (7)
Xenopus (3)
IHC (8)
IHC-P (2)
WB (28)
ELISA (7)
ICC (2)
IF (6)
IP (3)
Peptide-ELISA (1)
rabbit (28)
mouse (3)
IgG (18)
IgG1 (1)
IgG2a,k (2)
monoclonal mc (3)
polyclonal pc (28)
3G8 (1)
TBP7-27 (1)
APC (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (4)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (1)
Unconjugated (15)
N-Terminus (8)
aa1-418 (8)
aa1-419 (1)
aa1-50 (1)
aa368-418 (1)
No (38)
GST (1)
His-T7 (1)
Myc-DDK (Flag) (5)
Human (5)
293T Cells (2)
E. coli (1)
HEK 293 Cells (3)
Wheat Germ Extract (1)
Purified (1)
PSMC4 Antibody - Immunofluorescence analysis of U2OS cells.
Select
PSMC4 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
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PSMC4 Mouse anti-Human Monoclonal (aa1-419) (Azide-free) Antibody
Human
ELISA, ICC, IF, IHC, IHC-P, WB
Unconjugated, Azide-free
100 µg/$705
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PSMC4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$331
PSMC4 Antibody - Immunohistochemistry Dilution at 1:500 and staining in paraffin-embedded human adrenal gland tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal Goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated Secondary antibody and visualized using an HRP conjugated SP system.
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PSMC4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
Select
PSMC4 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
PSMC4 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
PSMC4 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
PSMC4 Antibody - Immunofluorescence of monoclonal antibody to PSMC4 on HepG2 cell. [antibody concentration 10 ug/ml]
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PSMC4 Mouse anti-Human Monoclonal (3G8) Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$423
PSMC4 Antibody - Immunofluorescent analysis of PSMC4 staining in U2OS cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark.
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PSMC4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
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PSMC4 Mouse anti-Human Monoclonal (TBP7-27) Antibody
Rabbit, Human
IHC, IP, WB
Unconjugated
100 µl/$560
PSMC4 Antibody - Detection of Human PSMC4 by Western Blot. Samples: Whole cell lysate from 293T (15 and 50 ug), HeLa (H; 50 ug), and Jurkat (J; 50 ug) cells. Antibodies: Affinity purified rabbit anti-PSMC4 antibody used for WB at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.
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PSMC4 Rabbit anti-Human Polyclonal (aa1-50) Antibody
Human
IHC, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
PSMC4 Antibody - Detection of Human PSMC4 by Western Blot. Samples: Whole cell lysate from 293T (15 and 50 ug), HeLa (H; 50 ug), and Jurkat (J; 50 ug) cells. Antibodies: Affinity purified rabbit anti-PSMC4 antibody used for WB at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.
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PSMC4 Rabbit anti-Human Polyclonal (aa368-418) Antibody
Human
IHC, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
PSMC4 Antibody - 1:100 staining rat brain tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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PSMC4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
PSMC4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
50 µl/$356; 100 µl/$461
PSMC4 Antibody - PSMC4 / TBP7 antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PSMC4 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
PSMC4 Antibody - PSMC4 / TBP7 antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
PSMC4 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Rabbit, Dog, Bovine, Rat, Chimpanzee, Gibbon, Human, Monkey
WB
HRP Conjugated
100 µl/$469
PSMC4 Antibody - PSMC4 / TBP7 antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
PSMC4 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Rabbit, Dog, Bovine, Rat, Chimpanzee, Gibbon, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
PSMC4 Antibody - PSMC4 / TBP7 antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
PSMC4 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Rabbit, Dog, Bovine, Rat, Chimpanzee, Gibbon, Human, Monkey
WB
FITC Conjugated
100 µl/$469
PSMC4 Antibody - PSMC4 / TBP7 antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
PSMC4 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$424
PSMC4 Antibody - PSMC4 / TBP7 antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
PSMC4 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Xenopus, Bat, Rat, Rabbit, Mouse, Dog, Guinea pig, Bovine, Horse, Human, Monkey, Chimpanzee, Gibbon
WB
HRP Conjugated
100 µl/$469
PSMC4 Antibody - PSMC4 / TBP7 antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
PSMC4 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Xenopus, Bat, Rat, Rabbit, Mouse, Dog, Guinea pig, Bovine, Horse, Human, Monkey, Chimpanzee, Gibbon
WB
Biotin Conjugated
100 µl/$469
PSMC4 Antibody - PSMC4 / TBP7 antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
PSMC4 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Xenopus, Bat, Rat, Rabbit, Mouse, Dog, Guinea pig, Bovine, Horse, Human, Monkey, Chimpanzee, Gibbon
WB
FITC Conjugated
100 µl/$469
PSMC4 Antibody - Western blot of recombinant PSMC4 / TBP7.
Select
PSMC4 Rabbit anti-Human Polyclonal (aa1-418) Antibody
Rat, Pig, Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
PSMC4 Antibody - Western blot of recombinant PSMC4 / TBP7.
Select
PSMC4 Rabbit anti-Human Polyclonal (aa1-418) (Biotin) Antibody
Rat, Pig, Human
WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348
PSMC4 Antibody - Anti-PSMC4 rabbit polyclonal antibody at 1:500 dilution. Lane A: HepG2 Whole Cell Lysate. Lane B: Jurkat Whole Cell Lysate. Lane C: 293T Whole Cell Lysate. Lane D: A549 Whole Cell Lysate. Lysates/proteins at 30 ug per lane. Secondary: Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size: 47 kDa.
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PSMC4 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µl/$412
Viewing 1-25 of 38 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).