PSMC1

proteasome (prosome, macropain) 26S subunit, ATPase, 1

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit and a 20S core alpha subunit interact specifically with the hepatitis B virus X protein, a protein critical to viral replication. This subunit also interacts with the adenovirus E1A protein and this interaction alters the activity of the proteasome. Finally, this subunit interacts with ataxin-7, suggesting a role for the proteasome in the development of spinocerebellar ataxia type 7, a progressive neurodegenerative disorder.

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Products

Antibodies (24)

Proteins (4)

ELISA Kits (1)

Type

Over-Expression Lysate (2)

Primary (24)

Recombinant (2)

Sandwich (1)

Target

PSMC1 (29)

Reactivity

Human (23)

Mouse (22)

Rat (9)

Bat (6)

Bovine (6)

Chicken (6)

Chimpanzee (6)

Dog (6)

Drosophila (3)

Gibbon (6)

Guinea pig (6)

Horse (6)

Monkey (7)

Pig (6)

Rabbit (6)

Xenopus (6)

Zebrafish (6)

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Application

IHC (3)

IHC-P (1)

WB (24)

Flo (1)

ELISA (2)

ICC (1)

IF (1)

IP (1)

Peptide-ELISA (1)

Host

rabbit (23)

mouse (1)

Isotype

IgG (5)

IgG1 (1)

Clonality

monoclonal mc (1)

polyclonal pc (23)

Clone

5B6 (1)

Format

96-Well Strip Plate (1)

APC (1)

APC Conjugated (1)

Biotin Conjugated (3)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (1)

Unconjugated (11)

Epitope

aa1-440 (8)

aa269-318 (4)

aa71-120 (4)

aa390-440 (1)

aa408-436 (1)

aa50-100 (1)

Publications

No (29)

Sample Type

Plasma (1)

Serum (1)

Tag

His-T7 (1)

Myc-DDK (Flag) (3)

Species

Human (3)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Select

PSMC1 Antibody (aa390-440) LS-C290471

Antibody:

PSMC1 Rabbit anti-Human Polyclonal (aa390-440) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

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PSMC1 Antibody (clone 5B6) LS-C758809

Antibody:

PSMC1 Mouse anti-Human Monoclonal (5B6) Antibody

Reactivity:

Mouse, Human

Applications:

Flo, ICC, IF, IHC, WB

Format:

Unconjugated

Price:

100 µl/$541

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PSMC1 Antibody LS-C401947

Antibody:

PSMC1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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PSMC1 Antibody (aa1-440) LS-C314952

Antibody:

PSMC1 Rabbit anti-Human Polyclonal (aa1-440) Antibody

Reactivity:

Mouse, Human

Applications:

IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225

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PSMC1 Antibody (aa1-440, HRP) LS-C712398

Antibody:

PSMC1 Rabbit anti-Human Polyclonal (aa1-440) (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$338; 200 µl/$393; 500 µl/$575; 1 ml/$702; 2 ml/$939; 5 ml/$1,593

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PSMC1 Antibody (aa1-440, Biotin) LS-C687794

Antibody:

PSMC1 Rabbit anti-Human Polyclonal (aa1-440) (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348

Select

PSMC1 Antibody (aa1-440, FITC) LS-C694691

Antibody:

PSMC1 Rabbit anti-Human Polyclonal (aa1-440) (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$348; 200 µl/$407; 500 µl/$605; 1 ml/$755; 2 ml/$993; 5 ml/$1,716

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PSMC1 Antibody (aa1-440, APC) LS-C718272

Antibody:

PSMC1 Rabbit anti-Human Polyclonal (aa1-440) (APC) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451

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PSMC1 Antibody (aa1-440, APC, Cy7) LS-C735387

Antibody:

PSMC1 Rabbit anti-Human Polyclonal (aa1-440) (APC, Cy7) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

APC, Cy7 Conjugated

Price:

100 µl/$505; 200 µl/$648; 500 µl/$1,152; 1 ml/$1,401; 2 ml/$1,961; 5 ml/$3,676

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PSMC1 Antibody (aa1-440, Cy3) LS-C703375

Antibody:

PSMC1 Rabbit anti-Human Polyclonal (aa1-440) (Cy3) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Cy3 Conjugated

Price:

100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451

Select

PSMC1 Antibody (aa1-440, PE) LS-C726459

Antibody:

PSMC1 Rabbit anti-Human Polyclonal (aa1-440) (PE) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451

• Unconjugated
• HRP
• Biotin
• FITC
• APC
• APC, Cy7
• Cy3
• More...
  • PE

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • APC
  • APC, Cy7
  • Cy3
  • PE

Select

PSMC1 Antibody LS-C752202

Antibody:

PSMC1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$331

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PSMC1 Antibody LS-C803118

Antibody:

PSMC1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

PSMC1 Antibody (aa269-318) LS-C135384

Antibody:

PSMC1 Rabbit anti-Mouse Polyclonal (aa269-318) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

PSMC1 Antibody (aa269-318, HRP) LS-C461814

Antibody:

PSMC1 Rabbit anti-Mouse Polyclonal (aa269-318) (HRP) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Drosophila, Pig, Horse, Bat, Rat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

PSMC1 Antibody (aa269-318, Biotin) LS-C461812

Antibody:

PSMC1 Rabbit anti-Mouse Polyclonal (aa269-318) (Biotin) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Drosophila, Pig, Horse, Bat, Rat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

PSMC1 Antibody (aa269-318, FITC) LS-C461813

Antibody:

PSMC1 Rabbit anti-Mouse Polyclonal (aa269-318) (FITC) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Drosophila, Pig, Horse, Bat, Rat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

PSMC1 Antibody (aa71-120) LS-C146282

Antibody:

PSMC1 Rabbit anti-Mouse Polyclonal (aa71-120) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

PSMC1 Antibody (aa71-120, HRP) LS-C461811

Antibody:

PSMC1 Rabbit anti-Mouse Polyclonal (aa71-120) (HRP) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Pig, Horse, Bat, Rat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

PSMC1 Antibody (aa71-120, Biotin) LS-C461809

Antibody:

PSMC1 Rabbit anti-Mouse Polyclonal (aa71-120) (Biotin) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Pig, Horse, Bat, Rat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

PSMC1 Antibody (aa71-120, FITC) LS-C461810

Antibody:

PSMC1 Rabbit anti-Mouse Polyclonal (aa71-120) (FITC) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Pig, Horse, Bat, Rat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

PSMC1 Antibody (aa50-100) LS-C290466

Antibody:

PSMC1 Rabbit anti-Human Polyclonal (aa50-100) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

PSMC1 Antibody (aa408-436) LS-C203998

Antibody:

PSMC1 Rabbit anti-Human Polyclonal (aa408-436) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Select

PSMC1 Antibody LS-C343765

Antibody:

PSMC1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

25 µl/$316

Select

Human PSMC1 (Sandwich ELISA) ELISA Kit - LS-F39594

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

6.25 - 400 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$814

Viewing 1-25 of 29 product results

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