PSENEN / PEN-2

presenilin enhancer gamma secretase subunit

Presenilins, which are components of the gamma-secretase protein complex, are required for intramembranous processing of some type I transmembrane proteins, such as the Notch proteins and the beta-amyloid precursor protein. Signaling by Notch receptors mediates a wide range of developmental cell fates. Processing of the beta-amyloid precursor protein generates neurotoxic amyloid beta peptides, the major component of senile plaques associated with Alzheimer's disease. This gene encodes a protein that is required for Notch pathway signaling, and for the activity and accumulation of gamma-secretase. Mutations resulting in haploinsufficiency for this gene cause familial acne inversa-2 (ACNINV2). Alternative splicing results in multiple transcript variants.

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Antibodies (18)

ELISA Kits (4)

Proteins (4)

Type

Custom (1)

Over-Expression Lysate (2)

Primary (18)

Recombinant (2)

Sandwich (3)

Target

PSENEN / PEN-2 (26)

Reactivity

Human (18)

Mouse (16)

Rat (12)

Bat (7)

Bovine (6)

Chimpanzee (3)

Dog (8)

Gibbon (6)

Guinea pig (6)

Horse (8)

Monkey (8)

Opossum (1)

Pig (7)

Rabbit (7)

Xenopus (3)

Zebrafish (3)

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Application

IHC (3)

IHC-P (1)

WB (17)

ELISA (3)

IF (3)

IP (1)

Peptide-ELISA (1)

Host

rabbit (17)

mouse (1)

Product Group

PathPlus Neuro (1)

Isotype

IgG (8)

Clonality

monoclonal mc (1)

polyclonal pc (17)

Clone

12K165 (1)

Format

96-Well Strip Plate (4)

Biotin Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

Unconjugated (12)

Epitope

C-Terminus (4)

aa20-69 (4)

Lys11 (1)

aa1-50 (1)

aa89-98 (1)

Publications

No (26)

Sample Type

Plasma (3)

Serum (3)

Tag

GST (1)

Myc-DDK (Flag) (3)

Species

Human (3)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

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PathPlus™ PSENEN / PEN-2 Antibody LS-B3207

Neuroscience

(5.0) Rating

Antibody:

PSENEN / PEN-2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.05 mg/$440

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PSENEN / PEN-2 Antibody (C-Terminus) LS-C135520

Antibody:

PSENEN / PEN-2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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PSENEN / PEN-2 Antibody (C-Terminus, HRP) LS-C466260

Antibody:

PSENEN / PEN-2 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Xenopus, Zebrafish, Pig, Horse, Rabbit, Mouse, Dog, Guinea pig, Bovine, Bat, Rat, Gibbon, Human, Monkey, Chimpanzee

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

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PSENEN / PEN-2 Antibody (C-Terminus, Biotin) LS-C466258

Antibody:

PSENEN / PEN-2 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Xenopus, Zebrafish, Pig, Horse, Rabbit, Mouse, Dog, Guinea pig, Bovine, Bat, Rat, Gibbon, Human, Monkey, Chimpanzee

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

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PSENEN / PEN-2 Antibody (C-Terminus, FITC) LS-C466259

Antibody:

PSENEN / PEN-2 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Xenopus, Zebrafish, Pig, Horse, Rabbit, Mouse, Dog, Guinea pig, Bovine, Bat, Rat, Gibbon, Human, Monkey, Chimpanzee

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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PSENEN / PEN-2 Antibody (aa20-69) LS-C145247

Antibody:

PSENEN / PEN-2 Rabbit anti-Mouse Polyclonal (aa20-69) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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PSENEN / PEN-2 Antibody (aa20-69, HRP) LS-C466263

Antibody:

PSENEN / PEN-2 Rabbit anti-Mouse Polyclonal (aa20-69) (HRP) Antibody

Reactivity:

Rabbit, Mouse, Dog, Guinea pig, Pig, Horse, Bat, Gibbon, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

PSENEN / PEN-2 Antibody (aa20-69, Biotin) LS-C466261

Antibody:

PSENEN / PEN-2 Rabbit anti-Mouse Polyclonal (aa20-69) (Biotin) Antibody

Reactivity:

Rabbit, Mouse, Dog, Guinea pig, Pig, Horse, Bat, Gibbon, Human, Monkey

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

PSENEN / PEN-2 Antibody (aa20-69, FITC) LS-C466262

Antibody:

PSENEN / PEN-2 Rabbit anti-Mouse Polyclonal (aa20-69) (FITC) Antibody

Reactivity:

Rabbit, Mouse, Dog, Guinea pig, Pig, Horse, Bat, Gibbon, Human, Monkey

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

PSENEN / PEN-2 Antibody LS-C19652

Antibody:

PSENEN / PEN-2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

0.1 mg/$460

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PSENEN / PEN-2 Antibody LS-C803762

Antibody:

PSENEN / PEN-2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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PSENEN / PEN-2 Antibody LS-C2835

Antibody:

PSENEN / PEN-2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rabbit, Mouse, Dog, Bovine, Rat, Pig, Horse, Bat, Human, Monkey

Applications:

IHC, IP, WB

Format:

Unconjugated

Price:

0.1 ml/$386

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PSENEN / PEN-2 Antibody LS-C92307

Antibody:

PSENEN / PEN-2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

40 µg/$485

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PSENEN / PEN-2 Antibody (aa89-98, clone 12K165) LS-C182936

Antibody:

PSENEN / PEN-2 Mouse anti-Human Monoclonal (aa89-98) (12K165) Antibody

Reactivity:

Human

Applications:

IHC

Format:

Unconjugated

Price:

100 µg/$884

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PSENEN / PEN-2 Antibody (Lys11) LS-C191217

Antibody:

PSENEN / PEN-2 Rabbit anti-Human Polyclonal (Lys11) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$688

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PSENEN / PEN-2 Antibody (aa1-50) LS-C148699

Antibody:

PSENEN / PEN-2 Rabbit anti-Human Polyclonal (aa1-50) Antibody

Reactivity:

Mouse, Dog, Bovine, Rat, Opossum, Horse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$386

Select

PSENEN / PEN-2 Antibody LS-C750142

Antibody:

PSENEN / PEN-2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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PSENEN / PEN-2 Antibody LS-C833458

Antibody:

PSENEN / PEN-2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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Mouse PSENEN / PEN-2 (Sandwich ELISA) ELISA Kit - LS-F66750

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Human PSENEN / PEN-2 (Sandwich ELISA) ELISA Kit - LS-F67027

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

Select

Bovine PSENEN / PEN-2 (Custom) ELISA Kit - LS-F66344

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Bovine

Price:

1 Plate/$783

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Rat PSENEN / PEN-2 (Sandwich ELISA) ELISA Kit - LS-F66939

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

Select

Human PSENEN / PEN-2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G87480

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

11.8 kDa

Price:

20 µg/$150

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Human PSENEN / PEN-2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G70572

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

11.8 kDa

Price:

20 µg/$1,107

Select

Human PSENEN / PEN-2 Protein (Recombinant GST) (Full Length) - LS-G34464

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

36.85 kDa

Price:

10 µg/$479; 25 µg/$670

Viewing 1-25 of 26 product results

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