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Anti-PSEN2 / Presenilin 2 Antibody (aa319-334) LS-C172226

Note: This antibody replaces LS-C312534

Ordering

Wt. Vol. Conc. Price
100 µg - - $295

LSBio (Direct) LSBio (Direct)
206-374-1102
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PSEN2 / Presenilin 2 Antibody LS-C172226 Images

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Immunohistochemistry
Western blot

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Rabbit Polyclonal to Human PSEN2 / Presenilin 2
Human, Rat
IHC - Paraffin, IHC - Frozen, Western blot
Unconjugated

Details

Human PSEN2 / Presenilin 2
Rabbit
Human, Rat (tested or 100% immunogen sequence identity)
Polyclonal
Immunoaffinity purified

Applications

IHC - Paraffin, IHC - Frozen, Western blot

Specificity and Use

PSEN2 / Presenilin 2 antibody was raised against synthetic peptide corresponding to a sequence at the middle region of human Presenilin-2 (319-334 aa), identical to the related mouse and rat sequence.
aa319-334
Human, rat No cross reactivity with other proteins.

Packaging

5 mg BSA, 0.9 mg sodium chloride, 0.2 mg sodium phosphate, 0.05 mg Thimerosal, 0.05 mg sodium azide
Short term +4°C; Long term -20°C
For research use only.

About PSEN2 / Presenilin 2

P49810 NM_000447 NP_000438.2

PSEN2 Antibody, AD3LP Antibody, AD4 Antibody, AD5 Antibody, AD3L Antibody, CMD1V Antibody, PS-2 Antibody, PSNL2 Antibody, PS2 Antibody, STM2 Antibody, Presenilin 2 Antibody, STM-2 Antibody, E5-1 Antibody, Presenilin-2 Antibody

Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1 or PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP.

Immunohistochemistry

Immunohistochemistry
 

Western blot

Western blot
 

Requested From: United States
Date Requested: 9/1/2015

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