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PRSS2 / Trypsin 2

protease, serine, 2 (trypsin 2)

PRSS2 / Trypsin 2 belongs to the trypsin family of serine proteases and encodes anionic trypsinogen. It is part of a cluster of trypsinogen genes that are located within the T cell receptor beta locus. Enzymes of this family cleave peptide bonds that follow lysine or arginine residues. This protein is found at high levels in pancreatic juice and its upregulation is a characteristic feature of pancreatitis. This protein has also been found to activate pro-urokinase in ovarian tumors, suggesting a function in tumor invasion. In addition, this enzyme is able to cleave across the type II collagen triple helix in rheumatoid arthritis synovitis tissue, potentially participating in the degradation of type II collagen-rich cartilage matrix. Alternative splicing results in multiple transcript variants.

Gene Name: protease, serine, 2 (trypsin 2)
Family/Subfamily: Protease , Serine S1
Synonyms: PRSS2, Anionic trypsinogen, Protease serine 2, Serine protease 2, Tesp4, TRY2, TRYP2, Trypsinogen 2, TRY8, Trypsin II, Trypsin-2, Trypsinogen II, Trypsin 2
Target Sequences: NM_002770 NP_002761.1 P07478

Publications (1)

1
Identification of trypsin-degrading commensals in the large intestine. Youxian Li , Eiichiro Watanabe , Yusuke Kawashima , Damian R Plichta, Zhujun Wang, Makoto Ujike, Qi Yan Ang, Runrun Wu, Munehiro Furuichi, Kozue Takeshita, Koji Yoshida, Keita Nishiyama, Sean M Kearney, Wataru Suda, Masahira Hattori, Satoshi Sasajima, Takahiro Matsunaga, Xiaoxi Zhang, Kazuto Watanabe, Jun Fujishiro, Jason M Norman, Bernat Olle, Shutoku Matsuyama, Ho Namkoong, Yoshifumi Uwamino, Makoto Ishii, Koichi Fukunaga, Naoki Hasegawa, Osamu Ohara, Ramnik J Xavier, Koji Atarashi, Kenya Hond. Nature. 2022 September;609:582-589. [Full Text Article] [PubMed:36071157] [PMC:PMC9477747] Related Antibodies: LS-B15726, LS-C296077.

☰ Filters
Antibodies (38)
ELISA Kits (12)
Proteins (7)
Custom (1)
Primary (38)
Recombinant (7)
Sandwich (10)
Sandwich CLIA (1)
PRSS2 / Trypsin 2 (57)
Human (32)
Mouse (13)
Rat (4)
Dog (4)
Monkey (2)
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Rabbit (1)
IHC (10)
IHC-P (3)
WB (29)
ELISA (18)
IP (1)
SDS-PAGE (1)
rabbit (37)
mouse (1)
Product Group
IHCPlus (2)
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IgG1 (1)
monoclonal mc (1)
polyclonal pc (37)
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96-Well Strip Plate (9)
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Azide-free (1)
Biotin Conjugated (5)
Cy3 Conjugated (2)
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FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (3)
Unconjugated (13)
aa24-241 (8)
aa29-240 (8)
aa80-108 (6)
aa16-247 (1)
aa79-108 (1)
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6His, N-terminus (1)
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Biologically active (1)
PRSS2 / Trypsin 2 Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
PRSS2 / Trypsin 2 Rabbit anti-Human Polyclonal (aa79-108) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$485
Select
PRSS2 / Trypsin 2 Rabbit anti-Human Polyclonal (aa80-108) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
Select
PRSS2 / Trypsin 2 Rabbit anti-Human Polyclonal (aa80-108) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
Select
PRSS2 / Trypsin 2 Rabbit anti-Human Polyclonal (aa80-108) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
Select
PRSS2 / Trypsin 2 Rabbit anti-Human Polyclonal (aa80-108) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
Select
PRSS2 / Trypsin 2 Rabbit anti-Human Polyclonal (aa80-108) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
PRSS2 / Trypsin 2 Antibody - Western blot of recombinant PRSS2 / Trypsin 2.
Select
PRSS2 / Trypsin 2 Rabbit anti-Mouse Polyclonal (aa29-240) Antibody
Mouse
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
PRSS2 / Trypsin 2 Antibody - Western blot of recombinant PRSS2 / Trypsin 2.
Select
PRSS2 / Trypsin 2 Rabbit anti-Mouse Polyclonal (aa29-240) (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$316; 200 µl/$361; 500 µl/$511; 1 ml/$587; 2 ml/$809; 5 ml/$1,317
PRSS2 / Trypsin 2 Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE), at a concentration of 10 ug/ml.
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PRSS2 / Trypsin 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
PRSS2 / Trypsin 2 Protein - Recombinant Protease, Serine 2 By SDS-PAGE
Select
E. coli
6His, N-terminus
26.6 kDa
10 µg/$277; 50 µg/$417; 100 µg/$667; 200 µg/$832; 1 mg/$1,922; 500 µg/$1,470; 5 mg/$2,913; 2 mg/$2,107
PRSS2 / Trypsin 2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
PRSS2 / Trypsin 2 Protein - Recombinant  Protease, Serine 2 By SDS-PAGE
Select
E. coli
His, N-Terminal
27.0 kDa
10 µg/$279; 50 µg/$430; 100 µg/$687; 200 µg/$857; 1 mg/$1,956; 500 µg/$1,499; 5 mg/$2,997; 2 mg/$2,142
PRSS2 / Trypsin 2 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
PRSS2 / Trypsin 2 ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Human
0.156 - 10 ng/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
PRSS2 / Trypsin 2 Antibody - Western blot analysis of extracts of mouse tissues.
Select
PRSS2 / Trypsin 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
PRSS2 / Trypsin 2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
PRSS2 / Trypsin 2 Antibody - PRSS2 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human pancreas tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
Select
PRSS2 / Trypsin 2 Rabbit anti-Human Polyclonal (aa80-108) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
PRSS2 / Trypsin 2 Antibody - Western blot of PRSS2 / Trypsin 2 antibody.
Select
PRSS2 / Trypsin 2 Rabbit anti-Human Polyclonal (aa24-241) Antibody
Pig, Human
WB
Unconjugated
100 µl/$303; 200 µl/$343; 500 µl/$476; 1 ml/$543; 2 ml/$715; 5 ml/$1,182
Select
PRSS2 / Trypsin 2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
Select
PRSS2 / Trypsin 2 Mouse anti-Human Monoclonal (aa16-247) Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$896
Select
PRSS2 / Trypsin 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
Select
PRSS2 / Trypsin 2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
PRSS2 / Trypsin 2 Antibody - Western blot analysis of Trypsin 2 expression in HT102 (A), SW620 (B), CT26 (C), PC12 (D) whole cell lysates.
Select
PRSS2 / Trypsin 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
Select
PRSS2 / Trypsin 2 Rabbit anti-Dog Polyclonal Antibody
Dog
ELISA
Unconjugated
50 µg/$294; 100 µg/$360
Select
PRSS2 / Trypsin 2 Rabbit anti-Human Polyclonal Antibody
Human
Unconjugated
100 µl/$357
Viewing 1-25 of 57 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).