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Properdin / CFP

complement factor properdin

Properdin / CFP is a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Gene Name: complement factor properdin
Synonyms: CFP, Complement factor P, Complement factor properdin, PFC, PFD, Properidin, BFD, Properdin, Properdin P factor, complement
Target Sequences: NM_002621 NP_002612.1 P27918

Publications (1)

1
Effects of immunoadsorption combined with membrane filtration on complement markers - results of a randomized, controlled, crossover study. Federica Defendi, Paolo Malvezzi, Farsad Eskandary, Jean-Yves Cesbron, Lionel Rostaing, Georg A Böhmig, Chantal Dumestre-Pérard. Transplant international : official journal of the European Society for Organ Transplantation. 2019 August;32:876-883. [Full Text Article] [PubMed:30901502] Related Antibodies: LS-C195843.

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Antibodies (73)
ELISA Kits (14)
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Properdin / CFP (101)
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Properdin / CFP Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Properdin / CFP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
Properdin / CFP Antibody - Anti-CFP / Properdin antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Properdin / CFP Rabbit anti-Human Polyclonal (aa35-84) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
Properdin / CFP Antibody - Anti-CFP / Properdin antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Properdin / CFP Rabbit anti-Human Polyclonal (aa35-84) (FITC) Antibody
Human, Chimpanzee
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
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Properdin / CFP Goat anti-Human Polyclonal Antibody
Human
ELISA, ID, WB
Unconjugated
1 ml/$479
Properdin / CFP ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
Properdin / CFP Protein - Recombinant Complement Factor P By SDS-PAGE
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E. coli
His, N-Terminal
18.4 kDa
10 µg/$288; 50 µg/$487; 100 µg/$780; 200 µg/$972; 1 mg/$2,109; 500 µg/$1,636; 5 mg/$3,403; 2 mg/$2,298
Properdin / CFP ELISA Kit
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Sandwich
96-Well Strip Plate
Human
15.63 - 1000 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$764
Properdin / CFP ELISA Kit
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Sandwich
96-Well Microplate
Human
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
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Properdin / CFP Mouse anti-Human Monoclonal Antibody
Human
ELISA, Func, IHC, IHC-Fr
Unconjugated
100 µg/$872
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Properdin / CFP Goat anti-Human Polyclonal Antibody
Human
ID
Unconjugated
1 ml/$351
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Properdin / CFP Goat anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IF
FITC Conjugated
1 ml/$438
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Properdin / CFP Rabbit anti-Human Polyclonal (aa197-223) Antibody
Human
Flo, WB
Unconjugated
200 µl/$734
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Properdin / CFP Rabbit anti-Human Polyclonal (aa197-223) (Biotin) Antibody
Human
ELISA, Flo, WB
Biotin Conjugated
200 µl/$952
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Properdin / CFP Rabbit anti-Human Polyclonal (aa197-223) (FITC) Antibody
Human
ELISA, Flo, WB
FITC Conjugated
200 µl/$952
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Properdin / CFP Rabbit anti-Human Polyclonal (aa197-223) (APC) Antibody
Human
ELISA, Flo, WB
APC Conjugated
200 µl/$952
Properdin / CFP Antibody - Western blot of CFP Antibody in CEM cell line lysates (35 ug/lane). CFP (arrow) was detected using the purified antibody.
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Properdin / CFP Rabbit anti-Human Polyclonal (aa197-223) Antibody
Human
Flo, WB
Unconjugated
400 µl/$393
Properdin / CFP Antibody - Western blot of recombinant Properdin / CFP.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Properdin / CFP Rabbit anti-Mouse Polyclonal (aa310-459) (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$311; 200 µl/$353; 500 µl/$496; 1 ml/$567; 2 ml/$769; 5 ml/$1,248
Properdin / CFP Antibody - Western blot of recombinant Properdin / CFP.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Properdin / CFP Rabbit anti-Mouse Polyclonal (aa54-217) (HRP) Antibody
Mouse
WB
HRP Conjugated
100 µl/$329; 200 µl/$379; 500 µl/$547; 1 ml/$649; 2 ml/$884; 5 ml/$1,475
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Properdin / CFP Mouse anti-Human Monoclonal Antibody
Human
Flo, IHC, IHC-Fr, RIA, WB
Unconjugated
100 µg/$516
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Properdin / CFP Mouse anti-Human Monoclonal (10-18) Antibody
Human
ELISA, IHC, IHC-Fr, WB
Unconjugated
0.1 mg/$568
Properdin / CFP Antibody - 1:100 staining human uterus tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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Properdin / CFP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Properdin / CFP ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
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Properdin / CFP Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, IHC-Fr
Unconjugated
100 µg/$807
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Properdin / CFP Mouse anti-Human Monoclonal (10-24) Antibody
Human
ELISA, IHC-Fr, WB
Unconjugated
0.1 mg/$536
Properdin / CFP Antibody - IHC analysis of CFP using anti-CFP antibody. CFP was detected in paraffin-embedded section of human cholangiocarcinoma tissue. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1µg/ml rabbit anti-CFP Antibody overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC) with DAB as the chromogen.
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Properdin / CFP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
Viewing 1-25 of 101 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).