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Anti-Properdin / CFP Antibody (clone 10-18) LS-C44985


Wt. Vol. Conc. Price
100 µg - 1 mg/ml $405
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular Properdin / CFP Antibodies

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Immunohistochemistry Image
Anti-Properdin / CFP Antibody (clone GF1) LS-C189945
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Mouse Monoclonal [clone 10-18] (IgG1) to Human Properdin / CFP
IHC - Frozen, ELISA, Functional Assay


Human Properdin / CFP
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [10-18]
Protein A purified


  • IHC - Frozen
  • Functional Assay

Specificity and Use

Properdin / CFP antibody was raised against native purified factor P from human serum.
Recognizes human factor P, a 53 kD glycosylated protein present in blood serum. Factor P binds to microbial surfaces and binds and stabilizes the complement component 3- and complement component 5-convertase enzyme complexes. C3b then acts as an opsonin or initiates the complement pathway again creating a positive feedback loop which acts only on the bacterial cell, leaving the host cells unharmed. Deficiency of factor P makes the host more susceptible to bacterial infections, particularly to Neisseria species and meningococcal infections. Is reported to inhibit the function of factor P. Removal of Sodium Azide is recommended prior to use in functional assays. XXX recommend the use of EQU003 for this purpose.


Borate buffered saline, pH 8.2, 0.02% sodium azide.
For research use only.

About Properdin / CFP

P27918 NM_002621 NP_002612.1

CFP Antibody, Complement factor P Antibody, Complement factor properdin Antibody, PFC Antibody, PFD Antibody, Properidin Antibody, BFD Antibody, Properdin Antibody, Properdin P factor, complement Antibody

Properdin / CFP is a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell.

Requested From: United States
Date Requested: 10/25/2016

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