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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PROKR1 Antibody (N‑Terminus) IHC‑plus™ LS‑A6684
PROKR1 antibody LS-A6684 is an unconjugated rabbit polyclonal antibody to human PROKR1. Validated for IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
Catalog
Size
Price
LS-A6684-50
50 µg (1 mg/ml)
Unavailable
In Stock for Immediate Shipment

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Product Description

PROKR1 antibody LS-A6684 is an unconjugated rabbit polyclonal antibody to human PROKR1. Validated for IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
About PROKR1
Receptor for prokineticin 1. Exclusively coupled to the G(q) subclass of heteromeric G proteins. Activation leads to mobilization of calcium, stimulation of phosphoinositide turnover and activation of p44/p42 mitogen-activated protein kinase. May play a role during early pregnancy. Q8TCW9 NM_138964 NP_620414.1

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Specifications

Target
Human PROKR1
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Monkey (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (7 - 16 µg/ml)
  • Western blot
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
PROKR1 antibody was raised against synthetic 15 amino acid peptide from N-terminal extracellular domain of human PROKR1. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Marmoset (93%); Elephant, Bovine (80%).
Blocking Peptide
LS-E29168 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-A6684. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
N-Terminus
Specificity
Human PROKR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Presentation
PBS, less than 0.1% sodium azide.
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

Publications (1)

1
Prokineticin 1 induces a pro-inflammatory response in murine fetal membranes but does not induce preterm delivery. Lannagan TR, Wilson MR, Denison F, Norman JE, Catalano RD, Jabbour HN. Reproduction (Cambridge, England). 2013 Dec;146:581-91. [Full Text Article] [PubMed:24051059] [PMC:PMC3805954]

Customer Reviews (0)


Images

Immunohistochemistry

Anti-PROKR1 antibody LS-A6684 IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PROKR1 antibody LS-A6684 IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Anti-PROKR1 antibody LS-A6684 IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PROKR1 antibody LS-A6684 IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Anti-PROKR1 antibody LS-A6684 IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PROKR1 antibody LS-A6684 IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Anti-PROKR1 antibody LS-A6684 IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PROKR1 antibody LS-A6684 IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Requested From: 
Date Requested: 7/19/2018

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