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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Prohibitin 2 / PHB2 Antibody (aa191‑240) LS‑C151440
PHB2 antibody LS-C151440 is an unconjugated rabbit polyclonal antibody to PHB2 (Prohibitin 2) from human, mouse, rat and other species. Validated for WB.
Catalog
Size
Price
LS-C151440-50
50 µg (1 mg/ml)
Unavailable

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Product Description

PHB2 antibody LS-C151440 is an unconjugated rabbit polyclonal antibody to PHB2 (Prohibitin 2) from human, mouse, rat and other species. Validated for WB.
About Prohibitin 2 / PHB2
Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases By similarity. Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging. Q99623 NM_007273 NP_001138303.1

PHB2 Antibody, BCAP37 Antibody, BAP Antibody, D-prohibitin Antibody, p22 Antibody, Prohibitin-2 Antibody, B-cell associated protein Antibody, Bap37 Antibody, PNAS-141 Antibody, Prohibitin 2 Antibody, REA Antibody


Specifications

Target
Mouse Prohibitin 2 / PHB2
Host
Rabbit
Reactivity
Mouse, Human, Monkey, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Rabbit, Xenopus (tested or 100% immunogen sequence identity)
Predicted
Chicken, Zebrafish, Drosophila (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot
  • (applications tested for the base form of this product only)
Immunogen
Synthetic peptide located between aa191-240 of mouse Phb2 (Q3V235, NP_031557). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Cat, Bovine, Bat, Rabbit, Horse, Opossum, Guinea pig, Xenopus, Catfish, Slime mold, Arabidopsis (100%); Orangutan, Turkey, Zebra finch, Chicken, Salmon, Sablefish, Stickleback, Zebrafish, Drosophila, Beetle (92%).
Blocking Peptide
LS-E22410 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C151440. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa191-240
Specificity
Mouse PHB2
Presentation
Lyophilized from PBS with 2% sucrose
Reconstitution
Distilled water
Storage
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Prohibitin 2 / PHB2 antibody Western Blot using Mouse Heart lysate at 1.0 ug/ml..  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Prohibitin 2 / PHB2 antibody Western Blot using Mouse Heart lysate at 1.0 ug/ml.. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Prohibitin 2 / PHB2 antibody Western Blot using Mouse Heart lysate at 1.0 ug/ml..  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Prohibitin 2 / PHB2 antibody Western Blot using Mouse Heart lysate at 1.0 ug/ml.. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Prohibitin 2 / PHB2 antibody Western Blot using Mouse Heart lysate at 1.0 ug/ml..  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Prohibitin 2 / PHB2 antibody Western Blot using Mouse Heart lysate at 1.0 ug/ml.. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Prohibitin 2 / PHB2 antibody Western Blot using Mouse Heart lysate at 1.0 ug/ml..  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Prohibitin 2 / PHB2 antibody Western Blot using Mouse Heart lysate at 1.0 ug/ml.. This image was taken for the unconjugated form of this product. Other forms have not been tested.


Requested From: 
Date Requested: 6/25/2018

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