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Anti-Prohibitin 2 / PHB2 Antibody (aa1-50) LS-C90864

Ordering

Wt. Vol. Conc. Price
100 µg - 1 mg/ml $545
Inquire for larger quantities

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Most Popular Prohibitin 2 / PHB2 Antibodies

Anti-Prohibitin 2 / PHB2 Antibody (C-Terminus) IHC-plus™ LS-B1889
Rabbit Polyclonal (IgG) to Mouse Prohibitin 2 / PHB2
Mouse, Human
IHC - Paraffin, ICC, Western blot
Unconjugated
Immunohistochemistry Image
Anti-Prohibitin 2 / PHB2 Antibody (aa1-50) LS-C90864
Rabbit Polyclonal to Human Prohibitin 2 / PHB2
Human
Immunoprecipitation
Unconjugated

100% Guaranteed 100% Guaranteed Publications Publications (1)
Rabbit Polyclonal to Human Prohibitin 2 / PHB2
Human
Immunoprecipitation
Unconjugated

Details

Human Prohibitin 2 / PHB2
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

Immunoprecipitation

Specificity and Use

Prohibitin 2 / PHB2 antibody was raised against the epitope recognized maps to a region between residues 1 and 50 of human Repressor of Estrogen Activity (Prohibitin 2) using the numbering given in entry NP_009204.1 (GeneID 11331).
aa1-50
Species cross-reactivity: This antibody cross-reacts with human. Other species have not been tested. Reactivity with mouse (and possibly X. laevis) is likely owing to conservation of sequence between these orthologs and human REA.
Suitable for use in Immunoprecipitation.

Packaging

Tris-citrate/phosphate buffer, pH 7-8, 0.09% sodium azide
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
For research use only.

Publications (1)

1
Identification of prohibitin and prohibiton as novel factors binding to the p53 induced gene 3 (PIG3) promoter (TGYCC)(15) motif. Guan X, Liu Z, Wang L, Johnson DG, Wei Q. Biochemical and biophysical research communications. 2014 Jan;443:1239-44. [Full Text Article] [PubMed:24388982] [PMC:PMC4155496]

About Prohibitin 2 / PHB2

Q99623 NM_007273 NP_001138303.1

PHB2 Antibody, BCAP37 Antibody, BAP Antibody, D-prohibitin Antibody, p22 Antibody, Prohibitin-2 Antibody, B-cell associated protein Antibody, Bap37 Antibody, PNAS-141 Antibody, Prohibitin 2 Antibody, REA Antibody

Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases By similarity. Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.

Requested From: United States
Date Requested: 12/7/2016

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