Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rat Monoclonal [clone M-58] (IgG1) to Human Procollagen Type I
IHC - Frozen
Human Procollagen Type I
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [M-58]
Tissue culture supernatant
IHC - Frozen
IHC - Paraffin
Specificity and Use
Human pro-collagen I.
Recognizes human pro-collagen I. Labels the amino-terminal pro-peptide. Localized intracellularly in cells producing pro-collagen I. Does not stain mature collagen fibers in tissue.
Suitable for use in Immunohistochemistry. Not recommended for Western Blot. Immunohistochemistry (Fresh frozen tissue sections): 1:10000-1:50000. Immunohistochemistry (Formaldehyde/formalin fixed paraffin sections): 1:100-1:1000; Pretreatment with 1% trypsin, 20 minutes at RT.
Supplied as a liquid
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.
About Procollagen Type I
Procollagen is the precursor of collagen, which is synthesized in osteoblasts and fibroblasts and subsequently exported from the cell and converted to collagen by procollagen peptidase.