Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rat Monoclonal [clone NOD-15] (IgG1) to Human Procollagen Type I
IHC, Western blot
Mouse Monoclonal [clone PCIDG10] (IgG1) to Human Procollagen Type I
Human, Bovine, Guinea pig
IHC - Paraffin
Human Procollagen Type I
Human, Bovine, Guinea pig (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [PCIDG10]
IHC - Paraffin (1:100)
Specificity and Use
Human pro-collagen I.
Labels carboxy-terminal pro-peptide of collagen type I. Does not stain mature collagen fibers in tissue, but rather is localized intracellularly in cells producing pro-collagen I. Species cross-reactivity: Human, guinea pig, bovine. Does not cross-react with mouse, rat, hamster.
Suitable for use in Immunohistochemistry. Immunohistochemistry: 1:100 (10-25 ug/ml); Paraffin embedded tissue sections fixed in acid EtOH, not traditional formalin. (1% HOC in 95% EtOH) fixation.
Ascites. No preservative added.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.
About Procollagen Type I
Procollagen is the precursor of collagen, which is synthesized in osteoblasts and fibroblasts and subsequently exported from the cell and converted to collagen by procollagen peptidase.