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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PRMT5 Antibody (aa60‑79) LS‑C9710
PRMT5 antibody LS-C9710 is an unconjugated rabbit polyclonal antibody to PRMT5 from human, mouse, rat and other species. Validated for IP and WB.
Antibody
Catalog
Size
Price
LS-C9710-200
200 µg
$755

Popular PRMT5 Products

Anti-PRMT5 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2433 dilution 1:100.
Species: Human, Monkey, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot, Immunoprecipitation
Antibody
Species: Human
Applications: Immunoprecipitation, ELISA
Immunohistochemistry of paraffin-embedded mouse brain using PRMT5 antibodyat dilution of 1:100 (40x lens).
Species: Human, Monkey, Mouse, Rat
Applications: IHC, Immunofluorescence, Western blot
PRMT5 antibody LS-C31716 was used in IHC to stain formalin-fixed, paraffin-embedded human lung.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Chimpanzee, Orangutan, Gibbon, Monkey, Mouse, Rat, Bat, Dog, Guinea pig, Horse, Pig, Rabbit, Zebrafish
Applications: IHC, IHC - Paraffin, Western blot
Antibody
Species: Human
Applications: IHC, Immunofluorescence, Western blot

Product Description

PRMT5 antibody LS-C9710 is an unconjugated rabbit polyclonal antibody to PRMT5 from human, mouse, rat and other species. Validated for IP and WB.
About PRMT5
Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Methylates SUPT5H. O14744 NM_006109 NP_006100.2

PRMT5 Antibody, 72 kDa ICln-binding protein Antibody, HRMT1L5 Antibody, JBP1 Antibody, Jak-binding protein 1 Antibody, IBP72 Antibody, SKB1Hs Antibody, SKB1 Antibody, SKB1 homolog Antibody, Skb1 (S. pombe) homolog Antibody, SKB1 homolog (S. pombe) Antibody


Specifications

Target
Human PRMT5
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Bat, Dog, Horse, Rabbit (tested or 100% immunogen sequence identity)
Predicted
Bovine, Chicken, Xenopus (at least 90% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Protein A purified
Modifications
Unmodified
Applications
  • Western blot
  • Immunoprecipitation
  • (applications tested for the base form of this product only)
Immunogen
PRMT5 antibody was raised against kLH-conjugated, synthetic peptide corresponding to aa60-79 (KNRPGPQTRSDLLLSGRDWN) of human protein arginine methyltransferase 5, SKB1 homolog. The immunizing sequence is identical in mouse. Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Elephant, Panda, Dog, Bat, Horse, Rabbit (100%); Xenopus, Bovine (95%); Chicken, Opossum (90%); Zebrafish, Pufferfish (85%); Medaka (80%).
Epitope
aa60-79
Specificity
Recognizes PRMT5, Mr ~70kD. Species cross-reactivity: Human and mouse.
Usage
Suitable for use in Western Blot and Immunoprecipitation. Immunoprecipitation: An independent laboratory has reported that this antibody immunoprecipitates active PRMT5 from HeLa cell lysate.
Presentation
0.1 M Tris-Glycine, pH 7.4, 0.15 M NaCl, 0.05% Sodium Azide, 30% Glycerol
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: United States
Date Requested: 8/17/2018

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