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Anti-PRMT5 Antibody (aa60-79) LS-C9710

Ordering

Wt. Vol. Conc. Price
200 µg - - $650
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular PRMT5 Antibodies

Anti-PRMT5 Antibody (aa50-100) LS-C89279
Rabbit Polyclonal to Human PRMT5
Human
Immunoprecipitation, ELISA
Unconjugated
Anti-PRMT5 Antibody (aa21-70, Biotin) LS-C439837
Rabbit Polyclonal (IgG) to Human PRMT5
Human, Chimpanzee, Orangutan, Gibbon, Monkey, Mouse, Rat, Bat, Dog, Guinea pig, Horse, Pig, Rabbit, Zebrafish
IHC - Paraffin, Western blot
Biotin Conjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human PRMT5
Human, Monkey, Mouse, Rat, Bat, Dog, Horse, Rabbit
Western blot, Immunoprecipitation
Unconjugated

Details

Human PRMT5
Rabbit
Human, Monkey, Mouse, Rat, Bat, Dog, Horse, Rabbit (tested or 100% immunogen sequence identity)
Bovine, Chicken, Xenopus (at least 90% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Protein A purified
Unmodified

Applications

  • Western blot
  • Immunoprecipitation

Specificity and Use

PRMT5 antibody was raised against kLH-conjugated, synthetic peptide corresponding to aa60-79 (KNRPGPQTRSDLLLSGRDWN) of human protein arginine methyltransferase 5, SKB1 homolog. The immunizing sequence is identical in mouse. Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Elephant, Panda, Dog, Bat, Horse, Rabbit (100%); Xenopus, Bovine (95%); Chicken, Opossum (90%); Zebrafish, Pufferfish (85%); Medaka (80%).
aa60-79
Recognizes PRMT5, Mr ~70kD. Species cross-reactivity: Human and mouse.
Suitable for use in Western Blot and Immunoprecipitation. Immunoprecipitation: An independent laboratory has reported that this antibody immunoprecipitates active PRMT5 from HeLa cell lysate.

Packaging

0.1 M Tris-glycine, pH 7.4, 0.15 M sodium chloride, 0.05% sodium azide, 30% glycerol.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About PRMT5

O14744 NM_006109 NP_006100.2

PRMT5 Antibody, 72 kDa ICln-binding protein Antibody, HRMT1L5 Antibody, JBP1 Antibody, Jak-binding protein 1 Antibody, IBP72 Antibody, SKB1Hs Antibody, SKB1 Antibody, SKB1 homolog Antibody, Skb1 (S. pombe) homolog Antibody, SKB1 homolog (S. pombe) Antibody

Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Methylates SUPT5H.

Requested From: United States
Date Requested: 12/10/2016

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