Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
Specificity and Use
PRMT5 antibody was raised against the epitope recognized maps to a region between residue 50 and 100 of Protein Arginine Methyltransferase 5 using the numbering given in entry NP_006100.2 (GeneID 10419).
Specific to the human PRMT5 protein. Species cross-reactivity: Human. Other species have not been tested.
Suitable for use in ELISA and Immunoprecipitation at 2-5 ug/mg of lysate.
Tris-citrate/phosphate buffer, pH 7 to 8
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C
PRMT5 Antibody, 72 kDa ICln-binding protein Antibody, HRMT1L5 Antibody, JBP1 Antibody, Jak-binding protein 1 Antibody, IBP72 Antibody, SKB1Hs Antibody, SKB1 Antibody, SKB1 homolog Antibody, Skb1 (S. pombe) homolog Antibody, SKB1 homolog (S. pombe) Antibody
Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Methylates SUPT5H.