PRMT1

protein arginine methyltransferase 1

Arginine methyltransferase that methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues present in proteins such as ESR1, histone H2, H3 and H4, PIAS1, HNRNPA1, HNRNPD, NFATC2IP, SUPT5H, TAF15 and EWS. Constitutes the main enzyme that mediates monomethylation and asymmetric dimethylation of histone H4 'Arg-4' (H4R3me1 and H4R3me2a, respectively), a specific tag for epigenetic transcriptional activation. Together with dimethylated PIAS1, represses STAT1 transcriptional activity, in the late phase of interferon gamma (IFN-gamma) signaling. May be involved in the regulation of TAF15 transcriptional activity, act as an activator of estrogen receptor (ER)-mediated transactivation, play a key role in neurite outgrowth and act as a negative regulator of megakaryocytic differentiation, by modulating p38 MAPK pathway. Methylates FOXO1 and retains it in the nucleus increasing its transcriptional activity.

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Products

Antibodies (43)

Proteins (12)

ELISA Kits (4)

Type

Custom (3)

Over-Expression Lysate (6)

Primary (43)

Recombinant (6)

Sandwich (1)

Target

PRMT1 (59)

Reactivity

Human (45)

Mouse (21)

Rat (12)

Bat (3)

Bovine (4)

Chimpanzee (3)

Dog (6)

Guinea pig (3)

Hamster (4)

Horse (4)

Monkey (2)

Orangutan (3)

Pig (3)

Rabbit (6)

Xenopus (3)

Zebrafish (3)

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Application

IHC (27)

IHC-P (12)

WB (35)

ELISA (19)

ICC (2)

IF (3)

IP (3)

Peptide-ELISA (1)

Host

rabbit (38)

mouse (5)

Product Group

IHCPlus (5)

Isotype

IgG (34)

IgG1,k (1)

IgG2b (1)

Clonality

monoclonal mc (5)

polyclonal pc (38)

Clone

4B12 (1)

Format

96-Well Strip Plate (4)

APC Conjugated (2)

Biotin Conjugated (5)

FITC Conjugated (5)

HRP Conjugated (5)

PE Conjugated (2)

Unconjugated (24)

Epitope

aa316-347 (7)

aa171-220 (4)

aa20-353 (2)

aa300-C-term (2)

C-Terminus (1)

N-Terminus (1)

aa1-50 (1)

aa298-318 (1)

aa317-346 (1)

Publications

No (59)

Sample Type

Cell Lysates (1)

Tissue Homogenates (1)

Tag

GST, N-terminus (1)

His (3)

Myc-DDK (Flag) (8)

Species

Human (8)

Mouse (1)

Source

293T Cells (3)

E. coli (3)

HEK 293 Cells (5)

Wheat Germ Extract (1)

Purification

Purified (2)

Low Endotoxin Level

Low endotoxin level (1)

Biologically Active

Biologically active (2)

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PRMT1 Antibody (clone 4B12) LS-C153340

Antibody:

PRMT1 Mouse anti-Human Monoclonal (4B12) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$440; 100 µg/$468

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PRMT1 Antibody (aa171-220) LS-C31577

Antibody:

PRMT1 Rabbit anti-Human Polyclonal (aa171-220) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$397

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Human PRMT1 (Sandwich ELISA) ELISA Kit - LS-F55019

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$834

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IHC-plus™ PRMT1 Antibody (aa300-C-term) LS-B12207

(4.0) Rating

Antibody:

PRMT1 Rabbit anti-Human Polyclonal (aa300-C-term) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µl/$460

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IHC-plus™ PRMT1 Antibody (aa1-50) LS-B12206

(4.0) Rating

Antibody:

PRMT1 Rabbit anti-Human Polyclonal (aa1-50) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µl/$460

Select

IHC-plus™ PRMT1 Antibody (aa317-346) LS-B3620

(4.0) Rating

Antibody:

PRMT1 Rabbit anti-Human Polyclonal (aa317-346) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

200 µl/$460

Select

PRMT1 Antibody LS-C484644

Antibody:

PRMT1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC, IHC-P

Format:

Unconjugated

Price:

100 µl/$412

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PRMT1 Antibody (N-Terminus) LS-C38316

Antibody:

PRMT1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

ELISA, ICC, IF, IP, WB

Format:

Unconjugated

Price:

100 µl/$688

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IHC-plus™ PRMT1 Antibody (aa300-C-term) LS-B12400

(4.0) Rating

Antibody:

PRMT1 Rabbit anti-Human Polyclonal (aa300-C-term) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$485

Select

IHC-plus™ PRMT1 Antibody (aa316-347) LS-B3619

(4.0) Rating

Antibody:

PRMT1 Rabbit anti-Human Polyclonal (aa316-347) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

200 µl/$460

Select

PRMT1 Antibody (aa20-353) LS-C379230

Antibody:

PRMT1 Rabbit anti-Human Polyclonal (aa20-353) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

Select

PRMT1 Antibody LS-C211859

Antibody:

PRMT1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

PRMT1 Antibody (HRP) LS-C211905

Antibody:

PRMT1 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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PRMT1 Antibody (Biotin) LS-C211904

Antibody:

PRMT1 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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PRMT1 Antibody (FITC) LS-C211899

Antibody:

PRMT1 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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PRMT1 Antibody (aa316-347) LS-C328302

Antibody:

PRMT1 Rabbit anti-Human Polyclonal (aa316-347) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

PRMT1 Antibody (aa316-347, HRP) LS-C548894

Antibody:

PRMT1 Rabbit anti-Human Polyclonal (aa316-347) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated

Price:

200 µl/$952

Select

PRMT1 Antibody (aa316-347, Biotin) LS-C528806

Antibody:

PRMT1 Rabbit anti-Human Polyclonal (aa316-347) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

PRMT1 Antibody (aa316-347, APC) LS-C281181

Antibody:

PRMT1 Rabbit anti-Human Polyclonal (aa316-347) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

PRMT1 Antibody (aa316-347, PE) LS-C281183

Antibody:

PRMT1 Rabbit anti-Human Polyclonal (aa316-347) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• HRP
• Biotin
• APC
• PE

• Unconjugated
• HRP
• Biotin
• More...
  • APC
  • PE

Select

PRMT1 Antibody LS-C752733

Antibody:

PRMT1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

Select

PRMT1 Antibody LS-C501667

Antibody:

PRMT1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

PRMT1 Antibody (aa20-353) LS-C379232

Antibody:

PRMT1 Rabbit anti-Human Polyclonal (aa20-353) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

Select

PRMT1 Antibody LS-C806026

Antibody:

PRMT1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

PRMT1 Antibody LS-C331224

Antibody:

PRMT1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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