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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PRMT1 Antibody (aa298‑318) LS‑C9702
Antibody
PRMT1 antibody LS-C9702 is an unconjugated rabbit polyclonal antibody to PRMT1 from human, mouse, rat and other species. Validated for WB.
Catalog
Size
Price
LS-C9702-200
200 µg
Unavailable

Popular PRMT1 Products

PRMT1 antibody LS-C31577 was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit, Xenopus, Zebrafish
Applications: IHC, IHC - Paraffin, Western blot
Antibody
Species: Human
Applications: IHC, Western blot, ELISA
Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
Species: Human, Mouse, Rat, Bovine, Dog, Guinea pig, Horse, Pig
Applications: IHC, IHC - Paraffin, Immunofluorescence, Immunoprecipitation
Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)
Species: Human, Mouse, Rat, Bovine, Dog, Horse, Rabbit, Xenopus
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Species: Human, Mouse, Rat, Bovine, Dog, Horse, Rabbit, Xenopus
Applications: IHC, IHC - Paraffin, Immunofluorescence

Product Description

PRMT1 antibody LS-C9702 is an unconjugated rabbit polyclonal antibody to PRMT1 from human, mouse, rat and other species. Validated for WB.
About PRMT1
Arginine methyltransferase that methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues present in proteins such as ESR1, histone H2, H3 and H4, PIAS1, HNRNPA1, HNRNPD, NFATC2IP, SUPT5H, TAF15 and EWS. Constitutes the main enzyme that mediates monomethylation and asymmetric dimethylation of histone H4 'Arg-4' (H4R3me1 and H4R3me2a, respectively), a specific tag for epigenetic transcriptional activation. Q99873 NM_001536 NP_001527.3

PRMT1 Antibody, HRMT1L2 Antibody, HMT2 Antibody, ANM1 Antibody, HCP1 Antibody, IR1B4 Antibody


Specifications

Target
Human PRMT1
Host
Rabbit
Reactivity
Human, Mouse, Rat, Bovine, Dog, Hamster, Horse, Rabbit (tested or 100% immunogen sequence identity)
Predicted
Monkey, Xenopus (at least 90% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Protein A purified
Modifications
Unmodified
Applications
  • Western blot
  • (applications tested for the base form of this product only)
Immunogen
PRMT1 antibody was raised against kLH-conjugated, synthetic peptide corresponding to aa298-318 (KTGEEIFGTIGMRPNAKNNRD) of human protein arginine methyltransferase 1 (accession number CAA71765). The immunizing sequence is identical in mouse. Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Mouse, Rat, Hamster, Elephant, Panda, Porcine, Dog, Bovine, Horse, Rabbit, Opossum (100%); Xenopus (95%); Monkey (90%); Zebrafish, Stickleback, Pufferfish (86%); Salmon (81%).
Epitope
aa298-318
Specificity
Recognize the PRMT1 doublet, Mr ~42-44kD. A non-specific protein was also detected, Mr ~120kD. Species cross-reactivity: Human and mouse.
Usage
Suitable for use in Western Blot. Western Blot Analysis: 0.1-0.5 ug/ml of this lot detected PRMT1 in RIPA lysates from Jurkat and 3T3/A31, NIH 3T3, HeLa, and mouse ES cells.
Presentation
0.1 M Tris-glycine, pH 7.4, 0.15 M sodium chloride, 0.05% sodium azide, 30% glycerol.
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/22/2018

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