Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Rat liver prolactin receptor.
Recognizes the ligand binding site of rat prolactin receptor at ~42kD. Does not cross-react with prolactin receptors from other species or with growth hormone receptor.
Suitable for use in Immunocytochemistry, Immunohistochemistry, Western Blot and functional applications. Immunocytochemistry: 5 ug/ml. Immunohistochemistry: Frozen and paraffin sections. Western Blot: 1 ug/ml. Functional Application: Inhibits the interaction of prolactin with the receptor.
100 µl 40-50% glycerol, PBS.
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
This is a receptor for the anterior pituitary hormone prolactin (PRL). Acts as a prosurvival factor for spermatozoa by inhibiting sperm capacitation through suppression of SRC kinase activation and stimulation of AKT. Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling.