Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Sheep, Human, Rat, Cat, Dog
(tested or 100% immunogen sequence identity)
IHC - Paraffin (1:500 - 1:3000)
Immunofluorescence (1:20 - 1:40)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
PRL / Prolactin antibody was raised against native sheep PRL / Prolactin.
Recognizes ovine prolactin, a 229 amino acid ~23kD somatotropin that acts primarily on the mammary gland by promoting lactation, mammogenesis, mitogenesis and osmoregulation. Prolactin can also exist in an alternative glycosylated form increasing it's apparent molecular weight to ~25kD. Glycosylation also appears to negatively affect the potency of ovine prolactin in a variety of explant bioassays. Has been successfully used for the detection of prolactin in plasma of mice by ELISA.
ELISA: In a simple ELISA, with 400 ng of antigen coated per well, the 50% OD was 1:40K. The end point titer was observed at an antibody dilution of 1:5M, under the same conditions.
PBS, 0.09% Sodium Azide
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
PRL / Prolactin is the anterior pituitary hormone prolactin. This secreted hormone is a growth regulator for many tissues, including cells of the immune system. It may also play a role in cell survival by suppressing apoptosis, and it is essential for lactation. Alternative splicing results in multiple transcript variants that encode the same protein.