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Anti-PRKDC / DNA-PKcs Antibody (phospho-Thr2638) LS-C198887

Catalog Size Price
LS-C198887-50 50 µl Unavailable
LS-C198887-100 100 µl Unavailable

Most Popular PRKDC / DNA-PKcs Antibodies

Anti-PRKDC / DNA-PKcs Antibody (phospho-Thr2609) IHC-plus™ LS-B409
Rabbit Polyclonal to Human PRKDC / DNA-PKcs
Human
IHC, IHC - Paraffin, Western blot, ELISA
Unconjugated
Anti-DNA-PKcs antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B409 concentration 5 ug/ml.
Anti-PRKDC / DNA-PKcs Antibody (phospho-Thr2609, clone 10B1) LS-C41044
Mouse Monoclonal [clone 10B1] (IgG1) to Human PRKDC / DNA-PKcs
Human
Immunofluorescence
Unconjugated
Anti-PRKDC / DNA-PKcs Antibody (aa4061-4110) IHC-plus™ LS-B6857
Rabbit Polyclonal (IgG) to Human PRKDC / DNA-PKcs
Human, Mouse
IHC, IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Unconjugated
Anti-DNA-PKcs antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6857 dilution 1:200.
Anti-PRKDC / DNA-PKcs Antibody (phospho-Thr2609) LS-C336068
Rabbit Polyclonal (IgG) to Human PRKDC / DNA-PKcs
Human
Western blot
Unconjugated
Western blot analysis of extracts from K562 cells.
Anti-PRKDC / DNA-PKcs Antibody (phospho-Thr2647) LS-C368485
Rabbit Polyclonal to Human PRKDC / DNA-PKcs
Human, Monkey
IHC, IHC - Paraffin, ICC, Immunofluorescence, Western blot
Unconjugated
Immunohistochemical analysis of DNA-PKcs (pT2647) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.

100% Guaranteed
Rabbit Polyclonal (IgG) to Human PRKDC / DNA-PKcs
Human, Mouse
Immunofluorescence, ELISA
Unconjugated

Details

Human PRKDC / DNA-PKcs
Rabbit
Human, Mouse (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • Immunofluorescence (1:100 - 1:500)
  • ELISA (1:1000)

Specificity and Use

Synthetic peptide derived from human DNA-PK around the phosphorylation site of Thr2638.
pThr2638
DNA-PK (Phospho-Thr2638) Antibody detects endogenous levels of DNA-PK only when phosphorylated at threonine2638.

Packaging

PBS, pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Store at -20°C.
For research use only.

About PRKDC / DNA-PKcs

P78527 NM_006904 NP_008835.5

PRKDC Antibody, DNA-PK Antibody, DNAPK Antibody, DNPK1 Antibody, HYRC Antibody, HYRC1 Antibody, p350 Antibody, Scid Antibody, XRCC7 Antibody, DNA-PK catalytic subunit Antibody, DNA-PKcs Antibody, p460 Antibody, DNA-dependent protein kinase catalytic subunit Antibody

Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. Must be bound to DNA to express its catalytic properties. Promotes processing of hairpin DNA structures in V(D)J recombination by activation of the hairpin endonuclease artemis (DCLRE1C). The assembly of the DNA-PK complex at DNA ends is also required for the NHEJ ligation step.

Immunofluorescence

Immunofluorescence of HUVEC cells treated with serum 20% 30', using DNA-PK (Phospho-Thr2638) Antibody. The sample on the right was incubated with synthetic peptide.
Immunofluorescence of HUVEC cells treated with serum 20% 30', using DNA-PK (Phospho-Thr2638) Antibody. The sample on the right was incubated with synthetic peptide.

Requested From: 
Date Requested: 4/25/2018

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