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PRKAR2A

protein kinase, cAMP-dependent, regulatory, type II, alpha

cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. It may interact with various A-kinase anchoring proteins and determine the subcellular localization of cAMP-dependent protein kinase. This subunit has been shown to regulate protein transport from endosomes to the Golgi apparatus and further to the endoplasmic reticulum (ER).

Gene Name: protein kinase, cAMP-dependent, regulatory, type II, alpha
Family/Subfamily: Protein Kinase Non Catalytic , not assigned-Protein Kinase Non Catalytic
Synonyms: PRKAR2A, PKR2, PRKAR2
Target Sequences: BT007225 AAP35889.1 P13861

Publications (1)

1
Phosphorylation of the cAMP-dependent protein kinase (PKA) regulatory subunit modulates PKA-AKAP interaction, substrate phosphorylation, and calcium signaling in cardiac cells. Manni S, Mauban JH, Ward CW, Bond M. The Journal of biological chemistry. 2008 283:24145-54. (WB) [PubMed:18550536] [PMC:PMC2527120]

☰ Filters
Antibodies (37)
Proteins (6)
ELISA Kits (1)
Over-Expression Lysate (2)
Primary (37)
Recombinant (4)
Sandwich CLIA (1)
PRKAR2A (44)
Human (37)
Mouse (5)
Rat (6)
Bovine (3)
Dog (4)
Gibbon (3)
Horse (3)
Monkey (1)
Pig (3)
IHC (23)
IHC-P (10)
WB (33)
Flo (9)
ELISA (8)
IF (22)
IP (2)
Peptide-ELISA (3)
rabbit (20)
mouse (17)
IgG (13)
IgG1 (16)
IgG1,k (1)
monoclonal mc (17)
polyclonal pc (20)
6A9 (1)
OTI1A7 (2)
OTI1B4 (2)
OTI1C4 (2)
OTI1F8 (2)
OTI1G7 (2)
OTI4A3 (2)
OTI4H8 (2)
OTI5F1 (2)
12 x 8-Well Microstrips (1)
Biotin Conjugated (2)
Carrier-free (8)
FITC Conjugated (2)
HRP Conjugated (2)
Unconjugated (31)
aa185-234 (4)
aa50-100 (2)
10-90 aa, Internal (1)
Pro68 (1)
aa312-346 (1)
aa41-90 (1)
No (44)
Plasma (1)
Serum (1)
GST (1)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (3)
Human (5)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (2)
PRKAR2A Antibody - PRKAR2A antibody Western blot of Fetal Kidney lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PRKAR2A Rabbit anti-Human Polyclonal (aa185-234) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$424
PRKAR2A Antibody - Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-PRKAR2A mouse monoclonal antibody. (Dilution 1:50).
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PRKAR2A Mouse anti-Human Monoclonal (OTI5F1) Antibody
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
PRKAR2A Antibody - Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-PRKAR2A mouse monoclonal antibody. (Dilution 1:50).
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PRKAR2A Mouse anti-Human Monoclonal (Carrier-free) (OTI5F1) Antibody
Dog, Rat, Human, Monkey
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
PRKAR2A Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-PRKAR2A mouse monoclonal antibody.
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PRKAR2A Mouse anti-Human Monoclonal (OTI1F8) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
PRKAR2A Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-PRKAR2A mouse monoclonal antibody.
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PRKAR2A Mouse anti-Human Monoclonal (Carrier-free) (OTI1F8) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
PRKAR2A Antibody - Immunoperoxidase of monoclonal antibody to PRKAR2A on formalin-fixed paraffin-embedded human salivary gland. [antibody concentration 3 ug/ml]
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PRKAR2A Mouse anti-Human Monoclonal (6A9) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
100 µg/$423
PRKAR2A Antibody - IHC of paraffin-embedded Adenocarcinoma of colon tissue using anti-PRKAR2A mouse monoclonal antibody. (Dilution 1:50).
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PRKAR2A Mouse anti-Human Monoclonal (OTI1B4) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
PRKAR2A Antibody - IHC of paraffin-embedded Adenocarcinoma of colon tissue using anti-PRKAR2A mouse monoclonal antibody. (Dilution 1:50).
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PRKAR2A Mouse anti-Human Monoclonal (Carrier-free) (OTI1B4) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
PRKAR2A Antibody - IHC of paraffin-embedded Adenocarcinoma of colon tissue using anti-PRKAR2A mouse monoclonal antibody. (Dilution 1:50).
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PRKAR2A Mouse anti-Human Monoclonal (OTI4H8) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
PRKAR2A Antibody - IHC of paraffin-embedded Adenocarcinoma of colon tissue using anti-PRKAR2A mouse monoclonal antibody. (Dilution 1:50).
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PRKAR2A Mouse anti-Human Monoclonal (Carrier-free) (OTI4H8) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
PRKAR2A Antibody - IHC of paraffin-embedded breast tissue using anti-PRKAR2A mouse monoclonal antibody. (Dilution 1:50).
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PRKAR2A Mouse anti-Human Monoclonal (OTI4A3) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
PRKAR2A Antibody - IHC of paraffin-embedded breast tissue using anti-PRKAR2A mouse monoclonal antibody. (Dilution 1:50).
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PRKAR2A Mouse anti-Human Monoclonal (Carrier-free) (OTI4A3) Antibody
Human
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
PRKAR2A Antibody - IHC of paraffin-embedded Adenocarcinoma of colon tissue using anti-PRKAR2A mouse monoclonal antibody. (Dilution 1:50).
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PRKAR2A Mouse anti-Human Monoclonal (OTI1A7) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
PRKAR2A Antibody - IHC of paraffin-embedded Adenocarcinoma of colon tissue using anti-PRKAR2A mouse monoclonal antibody. (Dilution 1:50).
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PRKAR2A Mouse anti-Human Monoclonal (Carrier-free) (OTI1A7) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
PRKAR2A Antibody - Immunohistochemistry of paraffin-embedded human glioma cancer at dilution of 1:100
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PRKAR2A Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
PRKAR2A Antibody - IHC of paraffin-embedded Adenocarcinoma of ovary tissue using anti-PRKAR2A mouse monoclonal antibody. (Dilution 1:50).
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PRKAR2A Mouse anti-Human Monoclonal (OTI1C4) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
PRKAR2A Antibody - IHC of paraffin-embedded Adenocarcinoma of ovary tissue using anti-PRKAR2A mouse monoclonal antibody. (Dilution 1:50).
Select
PRKAR2A Mouse anti-Human Monoclonal (Carrier-free) (OTI1C4) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
PRKAR2A Antibody - IHC of paraffin-embedded prostate tissue using anti-PRKAR2A mouse monoclonal antibody. (Dilution 1:50).
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PRKAR2A Mouse anti-Human Monoclonal (OTI1G7) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
PRKAR2A Antibody - IHC of paraffin-embedded prostate tissue using anti-PRKAR2A mouse monoclonal antibody. (Dilution 1:50).
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PRKAR2A Mouse anti-Human Monoclonal (Carrier-free) (OTI1G7) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
PRKAR2A Antibody - Western blot of PKA IIalpha reg antibody
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PRKAR2A Rabbit anti-Human Polyclonal (10-90 aa, Internal) Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
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PRKAR2A Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IP, WB
Unconjugated
100 µg/$331
PRKAR2A Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
PRKAR2A Antibody - Western blot of PKA II reg (P68) pAb in extracts from 293 cells.
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PRKAR2A Rabbit anti-Human Polyclonal (Pro68) Antibody
Human
IF, IHC, WB
Unconjugated
50 µl/$321; 100 µl/$403
PRKAR2A Antibody - Immunohistochemistry of paraffin-embedded Human breast cancer tissue  using PRKAR2A Polyclonal Antibody at dilution of 1:50(×200)
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PRKAR2A Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
PRKAR2A Antibody - Staining 293 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
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PRKAR2A Rabbit anti-Human Polyclonal Antibody
Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Viewing 1-25 of 44 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).