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Anti-PRKACA + PRKACB Antibody (aa8-22) LS-C26170


Wt. Vol. Conc. Price
200 µg - - $495
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular PRKACA + PRKACB Antibodies

Anti-PRKACA + PRKACB Antibody (C-Terminus, clone EP2102Y) IHC-plus™ LS-B9373
Rabbit Monoclonal [clone EP2102Y] (IgG) to Human PRKACA + PRKACB
Human, Mouse, Rat
IHC - Paraffin, ICC, Western blot, Immunoprecipitation, Flow Cytometry
Immunohistochemistry Image
Anti-PRKACA + PRKACB Antibody (N-Terminus) IHC-plus™ LS-B11535
Rabbit Polyclonal to Human PRKACA + PRKACB
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit, Sheep, Xenopus, Zebrafish
IHC - Paraffin, Western blot
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human PRKACA + PRKACB
Human, Mouse, Rat, Bovine, Dog, Hamster, Pig, Sheep
Western blot


Human, Mouse, Rat, Bovine, Dog, Hamster, Pig, Sheep (tested or 100% immunogen sequence identity)
Monkey (at least 90% immunogen sequence identity)
IgG Polyclonal
Protein A purified


Western blot

Specificity and Use

PRKACA + PRKACB antibody was raised against 16 residue synthetic peptide (KKGSEQESVKEFLAK-C) based upon amino acids 8-22 of the human 41kD alpha isoform of the catalytic subunit of PKA. The immunizing sequence is identical in mouse, rat, hamster, bovine and porcine. Percent identity by BLAST analysis: Human, Gorilla, Monkey, Mouse, Rat, Sheep, Hamster, Elephant, Bovine, Dog, Pig (100%); Orangutan, Gibbon, Marmoset, Stickleback (93%); Xenopus, Catfish, Salmon, Pufferfish, Zebrafish (87%).
Recognizes PKA purified from bovine heart and recombinant human alpha isoform of PKA expressed in CHO cells. Species cross-reactivity: mouse, rat, hamster, bovine and porcine. Cross-reactivity with the beta-isoform of mammalian PKA is possible since it shares identity in 14 of 15 residues.
Suitable for use in Western Blot. Proteins were visualized using a goat anti-rabbit secondary antibody conjugated to HRP and a chemiluminescence detection system.


0.07 M Tris-glycine, pH 7.4, 0.105 M sodium chloride, 0.035% sodium azide, 30% glycerol.
For research use only.


P17612 NM_002730 NP_002721.1

PRKACA Antibody, PKA C-alpha Antibody, Pka calpha Antibody, PKACA Antibody

Phosphorylates a large number of substrates in the cytoplasm and the nucleus. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis. Phosphorylates CDC25B, ABL1, NFKB1, CLDN3, PSMC5/RPT6, PJA2, RYR2, RORA and VASP. RORA is activated by phosphorylation.

Western blot

Western blot
Rat heart microsomal preparation probed with 0.5 ug/ml of LS-C26170

Requested From: United States
Date Requested: 10/23/2016

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