Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone BMK-13] (IgG1) to Human PRG2 / Proteoglycan 2
Human PRG2 / Proteoglycan 2
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [BMK-13]
Specificity and Use
This ab is specific for eosinophol major basic protein irrespective of the stages of eosinophil activating and can be regarded as a "pan-eosinophil" marker. Reacts with Human. This antibody does not cross-react with horse, mouse, or rat MBP.
PBS, 10 mM sodium azide, 1 mg/ml BSA
Store at 4°C for short term applications. For long term storage, aliquot and store at -20°C.
PRG2 Antibody, BMPG Antibody, Bone marrow proteoglycan Antibody, Bone-marrow proteoglycan Antibody, Eosinophil major basic protein Antibody, MBP1 Antibody, Natural killer cell activator Antibody, Proteoglycan 2 Antibody, Proteoglycan 2 preproprotein Antibody
PRG2 / Proteoglycan 2 is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions.