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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PRG2 / Proteoglycan 2 Antibody (clone BMK‑13) LS‑C188701
Antibody
Proteoglycan 2 antibody LS-C188701 is an unconjugated mouse monoclonal antibody to Proteoglycan 2 (PRG2) from human, rat and guinea pig. Validated for ELISA and IHC.
Catalog
Size
Price
LS-C188701-100
100 µg (0.1 mg/ml)
Unavailable

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Product Description

Proteoglycan 2 antibody LS-C188701 is an unconjugated mouse monoclonal antibody to Proteoglycan 2 (PRG2) from human, rat and guinea pig. Validated for ELISA and IHC.
About PRG2 / Proteoglycan 2
PRG2 / Proteoglycan 2 is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. P13727 NM_002728 NP_002719.3

PRG2 Antibody, BMPG Antibody, Bone marrow proteoglycan Antibody, Bone-marrow proteoglycan Antibody, Eosinophil major basic protein Antibody, MBP1 Antibody, Natural killer cell activator Antibody, Proteoglycan 2 Antibody, Proteoglycan 2 preproprotein Antibody


Specifications

Target
Human PRG2 / Proteoglycan 2
Host
Mouse
Reactivity
Human, Rat, Guinea pig (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal [BMK-13]
Conjugations
Unconjugated
Purification
Purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:20 - 1:50)
  • IHC - Frozen (1:20 - 1:50)
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
This antibody reacts with eosinophil major basic protein from both resting and activated eosinophils. Weakly cross reacts with basophils. IHC-Fr: It is recommended that sections are fixed in a 1:1 mixture of acetone and methanol and air-dried for 1 hour. Good results may be achieved via staining with the APAAP method. IHC-P: This product requires enzymatic pre-treatment of paraffin sections prior to staining. Pepsin is recommended for this purpose. Heat-mediated antigen retrieval methods should not be used.
Presentation
PBS, 0.02% sodium azide, 0.1% BSA
Storage
4°C or -20°C, Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/19/2018

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