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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PRF1 / Perforin Antibody LS‑C86211
Antibody
Perforin antibody LS-C86211 is an unconjugated rabbit polyclonal antibody to rat Perforin (PRF1). Validated for WB.
Catalog
Size
Price
LS-C86211-200
200 µg
Unavailable

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Product Description

Perforin antibody LS-C86211 is an unconjugated rabbit polyclonal antibody to rat Perforin (PRF1). Validated for WB.
About PRF1 / Perforin
Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Plays an important role in killing other cells that are recognized as non-self by the immune system, e.g. in transplant rejection or some forms of autoimmune disease. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes. P14222 NM_005041 NP_005032.2

PRF1 Antibody, HPLH2 Antibody, Perforin Antibody, p1 Antibody, Perforin1 Antibody, PFP Antibody, Cytolysin Antibody, FLH2 Antibody, Perforin-1 Antibody


Specifications

Target
Rat PRF1 / Perforin
Host
Rabbit
Reactivity
Rat (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Modifications
Unmodified
Applications
  • Western blot
Immunogen
PRF1 / Perforin antibody was raised against e. coli-expressed rat perforin.
Specificity
Reacts with both rat and mouse perforin. Cross-reactivity to perforin of other species has not been tested.
Presentation
Lyophilized from 0.1% sodium azide
Reconstitution
Distilled water
Storage
Store at 4°C for short term applications. For long term storage, aliquot and store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/24/2018

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