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Anti-PRF1 / Perforin Antibody (clone 5B10) LS-C87866

Ordering

Wt. Vol. Conc. Price
- 0.1 ml - $275
- 0.5 ml - $585
- 1 ml - $855
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular PRF1 / Perforin Antibodies

Anti-PRF1 / Perforin Antibody (clone CB5.4) LS-C18632
Rat Monoclonal [clone CB5.4] (IgG2a) to Mouse PRF1 / Perforin
Mouse
IHC - Paraffin, IHC - Frozen, ICC, Western blot, Immunoprecipitation
Unconjugated
Anti-PRF1 / Perforin Antibody (clone 5B10) LS-C87866
Mouse Monoclonal [clone 5B10] (IgG1) to Human PRF1 / Perforin
Human
IHC - Paraffin
Unconjugated
Immunohistochemistry Image
Anti-PRF1 / Perforin Antibody (clone delta G9) LS-C134746
Mouse Monoclonal [clone delta G9] (IgG2b,k) to Human PRF1 / Perforin
Human
IHC - Frozen, Flow Cytometry
Unconjugated

100% Guaranteed 100% Guaranteed Publications Publications (1)
Mouse Monoclonal [clone 5B10] (IgG1) to Human PRF1 / Perforin
Human
IHC - Paraffin
Unconjugated

Details

Human PRF1 / Perforin
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [5B10]
Unconjugated
Unmodified

Applications

IHC - Paraffin (1:10 - 1:20)

Specificity and Use

PRF1 / Perforin antibody was raised against recombinant protein corresponding to C-terminal region of human perforin.
c-terminal

Packaging

0.09% sodium azide. Tissue Culture Supernatant
Stable for 24 months when stored at 2-8°C.
For research use only.

Publications (1)

1
The role of cytotoxic T cells in IgG4-related dacryoadenitis and sialadenitis, the so-called Mikulicz's disease. Tabeya T, Yamamoto M, Naishiro Y, Ishigami K, Shimizu Y, Yajima H, Suzuki C, Seki N, Takano K, Himi T, Imai K, Takahashi H, Shinomura Y. Modern rheumatology / the Japan Rheumatism Association. Nov;24:953-60. [Full Text Article] [PubMed:24593171]

About PRF1 / Perforin

P14222 NM_005041 NP_005032.2

PRF1 Antibody, HPLH2 Antibody, Perforin Antibody, p1 Antibody, Perforin1 Antibody, PFP Antibody, Cytolysin Antibody, FLH2 Antibody, Perforin-1 Antibody

Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Plays an important role in killing other cells that are recognized as non-self by the immune system, e.g. in transplant rejection or some forms of autoimmune disease. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes.

Immunohistochemistry

Immunohistochemistry
Formalin-fixed, paraffin-embedded human lymphoma stained with peroxidase-conjugate and AEC chromogen. Note granular cytoplasmic staining of lymphocytes.
 

Requested From: United States
Date Requested: 12/6/2016

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