Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human, Rat, Bat, Dog, Hamster, Horse
(tested or 100% immunogen sequence identity)
Monkey, Mouse, Bovine, Rabbit (at least 90% immunogen sequence identity)
KLH-conjugated, synthetic peptide corresponding to aa104-115 (LVSDPKRTIAQD) of human Peroxiredoxin 1. Percent identity by BLAST analysis: Human, Gibbon, Monkey, Rat, Hamster, Elephant, Panda, Dog, Bat, Horse (100%); Marmoset, Mouse, Water buffalo, Porcine, Bovine, Rabbit, Opossum (92%).
Recognizes Peroxiredoxin 1, Mr 21kD. Species cross-reactivity: Human. Predicted to cross-react with rat based on homology.
Suitable for use in Western Blot and Immunocytochemistry. Proteins were visualized using a goat anti-rabbit secondary antibody conjugated to HRP and a chemiluminescence detection system. Immunocytochemistry: Has been reported to detect Peroxiredoxin 1 in TSU-Pr1 cells.
0.05% Sodium Azide, 30% Glycerol
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H2O2.