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PRC1

protein regulator of cytokinesis 1

PRC1 is a protein that is involved in cytokinesis. The protein is present at high levels during the S and G2/M phases of mitosis but its levels drop dramatically when the cell exits mitosis and enters the G1 phase. It is located in the nucleus during interphase, becomes associated with mitotic spindles in a highly dynamic manner during mitosis, and localizes to the cell mid-body during cytokinesis. This protein has been shown to be a substrate of several cyclin-dependent kinases (CDKs). It is necessary for polarizing parallel microtubules and concentrating the factors responsible for contractile ring assembly. Alternative splicing results in multiple transcript variants.

Gene Name: protein regulator of cytokinesis 1
Synonyms: PRC1, ASE1
Target Sequences: NM_003981 NP_003972.1 O43663

☰ Filters
Antibodies (18)
Proteins (9)
Over-Expression Lysate (6)
Primary (18)
Recombinant (3)
PRC1 (27)
Human (18)
Mouse (2)
Rat (2)
IHC (3)
IHC-P (3)
WB (17)
ELISA (8)
ICC (2)
IF (4)
Peptide-ELISA (3)
rabbit (16)
mouse (2)
Product Group
IHCPlus (1)
IgG (13)
IgG2b (1)
IgG2b,k (1)
monoclonal mc (2)
polyclonal pc (16)
1D4B (1)
6G2 (1)
Preservative Free (2)
Unconjugated (18)
aa1-150 (1)
aa1-233 (1)
aa432-481 (1)
pThr481 (1)
No (27)
GST (1)
His,N-terminus (1)
Myc-DDK (Flag) (7)
Human (6)
293T Cells (3)
HEK 293 Cells (4)
Insect Cells (1)
Wheat Germ Extract (1)
Purified (1)
Low endotoxin level (1)
PRC1 Antibody - Anti-PRC1 antibody IHC staining of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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PRC1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
PRC1 Antibody - 1:100 staining mouse lung tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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PRC1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
PRC1 Antibody - Anti-PRC1 rabbit polyclonal antibody at 1:500 dilution. Lane A: HeLa Whole Cell Lysate. Lane B: Jurkat Whole Cell Lysate. Lane C: Raji Whole Cell Lysate. Lane D: MDA-MB231 Whole Cell Lysate. Lysates/proteins at 30 ug per lane. Secondary: Goat Anti-Rabbit IgG H&L (Dylight 800) at 1/10000 dilution. Developed using the Odyssey technique. Performed under reducing conditions. Predicted band size: 72 kDa. Observed band size: 68 kDa.
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PRC1 Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ICC, IF, IHC-P, WB
Unconjugated, Preservative Free
100 µl/$412
PRC1 Antibody - Immunochemical staining of human PRC1 in human brain with rabbit polyclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections.
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PRC1 Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ICC, IF, IHC-P
Unconjugated, Preservative Free
100 µl/$412
PRC1 Antibody - Western blot analysis of lysates from HeLa cells, using p-PRC1 (Phospho-Thr481) antibody.
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PRC1 Rabbit anti-Human Polyclonal (pThr481) Antibody
Human
ELISA, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
PRC1 Antibody - Immunohistochemistry of paraffin-embedded Human gastric tissue.
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PRC1 Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
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PRC1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$351
Select
PRC1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$331
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PRC1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
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PRC1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
PRC1 Antibody - Western blot analysis of KB and Hela, antibody was diluted at 500. Secondary antibody was diluted at 1:20000.
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PRC1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PRC1 Antibody - Western blot analysis of KB and HeLa lysate, antibody was diluted at 500. Secondary antibody was diluted at 1:20000.
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PRC1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PRC1 Antibody - Western blot analysis of lysates from HeLa cells, using PRC1 antibody.
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PRC1 Rabbit anti-Human Polyclonal (aa432-481) Antibody
Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
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PRC1 Mouse anti-Human Monoclonal (aa1-150) (1D4B) Antibody
Human
WB
Unconjugated
25 µg/$449; 100 µg/$603
PRC1 Antibody - Hela cell extracts were resolved by electrophoresis, transferred to nitrocellulose, and probed with monoclonal antibody reactive against PRC1 (clone 6G2). Proteins were visualized using a goat anti-mouse secondary conjugated to HRP and a chemiluminescence
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PRC1 Mouse anti-Human Monoclonal (6G2) Antibody
Human
WB
Unconjugated
25 µg/$279; 100 µg/$359
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PRC1 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
PRC1 Antibody
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PRC1 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$575
PRC1 Antibody - PRC1 antibody Western blot. All lanes: Anti PRC1 at 0.5 ug/ml. Lane 1: MCF-7 Whole Cell Lysate at 40 ug. Lane 2: SGC Whole Cell Lysate at 40 ug. Lane 3: HELA Whole Cell Lysate at 40 ug. Predicted band size: 75 kD, 80 kD. Observed band size: 75 kD, 80 kD.
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PRC1 Rabbit anti-Human Polyclonal (aa1-233) Antibody
Human
WB
Unconjugated
10 µg/$318; 100 µg/$470
PRC1 Protein - Purified recombinant protein PRC1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
71.5 kDa
20 µg/$1,107
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293T Cells
Myc-DDK (Flag)
71.5 kDa
20 µg/$150
PRC1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
66 kDa
20 µg/$215
PRC1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
70.1 kDa
20 µg/$215
PRC1 Protein - 12.5% SDS-PAGE of human PRC1 stained with Coomassie Blue
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Wheat Germ Extract
GST
93.94 kDa
2 µg/$439
Select
Insect Cells
His,N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
74 kDa
50 µg/$721
PRC1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
71.5 kDa
100 µg/$494
Viewing 1-25 of 27 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).