Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
Products
Antibodies
ELISA and Assay Kits
Research Areas
Infectious Disease
Resources
Purchasing
Reference Material
Contact Us
Locations
Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Telephone Numbers
Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565
Contact Us
Additional Contact Details
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
PR / Progesterone Receptor
progesterone receptor
The progesterone receptor, a NR3 Steroid Receptor, is induced in granulosa cells of preovulatory follicles in response to surges in luteinizing hormone. It is essential for ovulation and egg implantation. A decrease in expression of endometrial progesterone receptor results in infertility in women. This receptor mediates the progesterone-induced transcription of proteases including ADAMTS1 and cathepsin L. In breast cancer, progesterone receptors are associated with hormone dependence and prolonged survival. At least two alternatively spliced isoforms have been identified in human: hPR-A (94 kD) is 164 aa shorter than hPR-B (114 kD). In most cell contexts, hPR-B functions as a transcriptional activator of progesterone-responsive genes, whereas hPR-A functions as a transcriptional inhibitor of all steroid hormone receptors. hPR-A and hPR-B have been shown to regulate different sets of genes in human breast cancer cells. Some of these PR-regulated genes are implicated in breast cancer.
| Gene Name: | progesterone receptor |
| Family/Subfamily: | NHR , NR3 Steroid receptor |
| Synonyms: | PGR, NR3C3, PR, Progesterone receptor |
| Target Sequences: | NM_000926 AAS00096.1 P06401 |
Publications (7)
1
Multiplexed assessment of the Southwest Oncology Group-directed Intergroup Breast Cancer Trial S9313 by AQUA shows that both high and low levels of HER2 are associated with poor outcome. Harigopal M, Barlow WE, Tedeschi G, Porter PL, Yeh IT, Haskell C, Livingston R, Hortobagyi GN, Sledge G, Shapiro C, Ingle JN, Rimm DL, Hayes DF. The American journal of pathology. 2010 176:1639-47. (IHC)
[PubMed:20150438]
[PMC:PMC2843456]
2
Evaluation of uterine receptivity after gonadotropin releasing hormone agonist administration as an oocyte maturation trigger: a rodent model. Ezoe K, Murata N, Yabuuchi A, Kobayashi T, Kato K. Scientific reports. 2019 August;9:12519. [Full Text Article]
[PubMed:31467307]
[PMC:PMC6715633]
Related Antibodies: LS-B5236.
3
Immunohistochemistry in Investigative and Toxicologic Pathology. Kyathanahalli S Janardhan, Heather Jensen, Natasha P Clayton, Ronald A Herbert. Toxicologic pathology. 2018 July;46:488-510. [Full Text Article]
[PubMed:29966501]
[PMC:PMC6033701]
Related Antibodies: LS-B5236.
☰ Filters
Products
Antibodies
(243)
ELISA Kits
(25)
Proteins
(8)
Type
Cell-Based
(1)
Cell-Based Phosphorylation
(3)
Competitive EIA
(2)
Custom
(3)
DNA Binding
(1)
Over-Expression Lysate
(2)
Primary
(243)
Recombinant
(6)
Sandwich
(13)
Sandwich CLIA
(2)
Target
PR / Progesterone Receptor
(276)
Reactivity
Human
(240)
Mouse
(36)
Rat
(42)
Bovine
(3)
Chicken
(5)
Chimpanzee
(6)
Dog
(2)
Gibbon
(3)
Guinea pig
(3)
Horse
(1)
Monkey
(10)
Orangutan
(3)
Rabbit
(4)
Sheep
(1)
Application
IHC
(112)
IHC-Fr
(11)
IHC-P
(64)
WB
(203)
Flo
(10)
ELISA
(53)
ICC
(16)
IF
(46)
IP
(11)
Peptide-ELISA
(9)
Host
rabbit
(125)
mouse
(118)
Product Group
IHCPlus
(3)
Isotype
IgG
(76)
IgG1
(70)
IgG1,k
(18)
IgG2a
(10)
IgG2a,k
(1)
IgG2b
(13)
IgM
(1)
IgM,k
(1)
Clonality
monoclonal mc
(121)
polyclonal pc
(120)
recombinant monoclonal rmc
(2)
Clone
1064/E2
(1)
1A5
(1)
1A6
(1)
1B11
(1)
2C11F11
(2)
2C2
(1)
3E11
(1)
4D8
(1)
4E9
(1)
5D10
(1)
8A11H1
(2)
A21-W
(1)
ABT-PR
(1)
C262
(1)
EP2
(2)
N559
(2)
OTI11E8
(2)
OTI11G9
(2)
OTI12D1
(2)
OTI14G1
(2)
OTI15C1
(2)
OTI16H2
(2)
OTI18B12
(2)
OTI1B3
(2)
OTI1F8
(2)
OTI1G7
(2)
OTI20A1
(2)
OTI20A11
(2)
OTI24A2
(2)
OTI24D6
(2)
OTI26C2
(2)
OTI29A3
(2)
OTI2C2
(2)
OTI2E2
(2)
OTI2F8
(2)
OTI31D9
(2)
OTI34G6
(2)
OTI4A11
(2)
OTI4B3
(2)
OTI4C12
(2)
OTI4D5
(2)
OTI5C12
(2)
OTI5E8
(2)
OTI6E3
(2)
OTI7A9
(2)
OTI7G7
(2)
PGR/2694
(3)
PGSR17
(3)
PR484
(3)
PR500
(2)
PR501
(2)
RBT22
(2)
SPM566
(2)
UMAB135
(2)
UMAB136
(2)
UMAB137
(2)
X22-C
(1)
Y85
(1)
Z15
(2)
Format
12 x 8-Well Microstrips
(4)
96-Well Microplate
(7)
96-Well Strip Plate
(14)
AP Conjugated
(1)
APC
(2)
APC Conjugated
(7)
Azide-free
(11)
Biotin Conjugated
(13)
BSA-free
(6)
Carrier-free
(33)
Concentrated
(1)
Cy3 Conjugated
(2)
Cy7 Conjugated
(2)
FITC Conjugated
(12)
HRP Conjugated
(13)
PE Conjugated
(7)
Preservative Free
(1)
Ready-to-Use
(6)
Supernatant
(1)
Unconjugated
(186)
Epitope
aa1-298
(60)
aa349-377
(9)
N-Terminus
(8)
aa672-790
(8)
aa523-550
(7)
aa816-843
(7)
aa833-861
(7)
pSer294
(7)
pSer190
(6)
aa1-111
(5)
aa185-234
(4)
aa201-250
(4)
aa51-100
(4)
pSer400
(4)
Internal
(3)
340-420 aa
(2)
C-Terminus
(2)
aa1-101
(2)
aa551-564
(2)
130-210 aa
(1)
230-310 aa
(1)
Ab-294
(1)
Ala394
(1)
Amino Acid: 730-871
(1)
Amino Acid: 731-909
(1)
B Isoform
(1)
Ser190
(1)
Val184
(1)
aa161-210
(1)
aa18-112
(1)
aa261-310
(1)
aa350-400
(1)
aa371-420
(1)
aa536-553
(1)
aa595-933
(1)
aa919-933
(1)
p190
(1)
p400
(1)
pS190
(1)
pSer162
(1)
Publications
No
(274)
Yes
(2)
Sample Type
Adherent Cell Cultures
(4)
Cell Lysates
(2)
Nuclear Lysates
(1)
Plasma
(13)
Serum
(13)
Tissue Homogenates
(3)
Tag
GST, N-terminus
(1)
His
(1)
His, N-terminus
(1)
His-SUMO
(1)
His-T7
(1)
Myc-DDK (Flag)
(3)
Species
Human
(4)
Pig
(2)
Rat
(1)
Source
293T Cells
(1)
E. coli
(3)
HEK 293 Cells
(2)
Wheat Germ Extract
(1)
Yeast
(1)
PR / Progesterone Receptor Mouse anti-Human Monoclonal Antibody
Mouse, Rat, Human, Monkey
IF, IHC, IHC-P, IP, WB
Unconjugated
125 µl/$695
![PR / Progesterone Receptor Antibody - Immunoperoxidase of monoclonal antibody to PGR on formalin-fixed paraffin-embedded human breast cancer. [antibody concentration 3 ug/ml]](https://lsbio-7d62.kxcdn.com/image2/pr-progesterone-receptor-antibody-clone-4e9-ls-c133381/51454_4954690.jpg)
PR / Progesterone Receptor Mouse anti-Human Monoclonal (4E9) Antibody
Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
100 µg/$423
PR / Progesterone Receptor Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P
Unconjugated
50 µl/$485
Sandwich
96-Well Microplate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$798
PR / Progesterone Receptor Rabbit anti-Human Monoclonal (Concentrated) (Y85) Antibody
Human
IHC, IHC-Fr, IHC-P
Unconjugated, Concentrated
1 ml/$2,153
PR / Progesterone Receptor Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
PR / Progesterone Receptor Rabbit anti-Human Polyclonal (aa595-933) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
PR / Progesterone Receptor Mouse anti-Human Monoclonal (aa1-298) (Carrier-free) (OTI11E8) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
![PR / Progesterone Receptor Antibody - Immunoperoxidase of monoclonal antibody to PGR on formalin-fixed paraffin-embedded human endometrium. [antibody concentration 1.5 ug/ml]](https://lsbio-7d62.kxcdn.com/image2/pr-progesterone-receptor-antibody-clone-2c2-ls-c133378/51442_4954676.jpg)
PR / Progesterone Receptor Mouse anti-Human Monoclonal (2C2) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
100 µg/$423
PR / Progesterone Receptor Rabbit anti-Mouse Polyclonal (aa201-250) Antibody
Mouse
WB
Unconjugated
100 µl/$424
PR / Progesterone Receptor Mouse anti-Human Monoclonal (aa1-298) (OTI4B3) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$434
Sandwich
96-Well Strip Plate
Rat
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
Sandwich
12 x 8-Well Microstrips
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
PR / Progesterone Receptor Rabbit anti-Human Polyclonal (aa371-420) Antibody
Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
PR / Progesterone Receptor Rabbit anti-Human Polyclonal (aa261-310) Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
PR / Progesterone Receptor Mouse anti-Human Monoclonal Antibody
Human
IHC, IHC-Fr, IHC-P
Unconjugated
0.1 ml/$351; 0.5 ml/$588; 1 ml/$859
PR / Progesterone Receptor Mouse anti-Human Monoclonal (pSer294) Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
100 µl/$469
PR / Progesterone Receptor Mouse anti-Human Monoclonal (aa919-933) (C262) Antibody
Chicken, Bovine, Rabbit, Mouse, Dog, Rat, Horse, Human, Monkey
IP, WB
Unconjugated
0.05 mg/$429
![PR / Progesterone Receptor Antibody - Immunoperoxidase of monoclonal antibody to PGR on formalin-fixed paraffin-embedded human breast cancer. [antibody concentration 3 ug/ml]](https://lsbio-7d62.kxcdn.com/image2/pr-progesterone-receptor-antibody-clone-3e11-ls-c133377/51438_4954672.jpg)
PR / Progesterone Receptor Mouse anti-Human Monoclonal (3E11) Antibody
Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
100 µg/$423
![PR / Progesterone Receptor Antibody - Immunoperoxidase of monoclonal antibody to PGR on formalin-fixed paraffin-embedded human endometrium. [antibody concentration 1.5 ug/ml]](https://lsbio-7d62.kxcdn.com/image2/pr-progesterone-receptor-antibody-clone-1b11-ls-c133379/51446_4954677.jpg)
PR / Progesterone Receptor Mouse anti-Human Monoclonal (1B11) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
100 µg/$423
![PR / Progesterone Receptor Antibody - Immunoperoxidase of monoclonal antibody to PGR on formalin-fixed paraffin-embedded human breast cancer. [antibody concentration 3 ug/ml]](https://lsbio-7d62.kxcdn.com/image2/pr-progesterone-receptor-antibody-clone-5d10-ls-c133380/51449_4954683.jpg)
PR / Progesterone Receptor Mouse anti-Human Monoclonal (5D10) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
100 µg/$423
PR / Progesterone Receptor Rabbit anti-Human Monoclonal (EP2) Antibody
Human
IHC-Fr, IHC-P
Unconjugated
0.1 ml/$448; 0.5 ml/$941; 1 ml/$1,288
PR / Progesterone Receptor Rabbit anti-Human Monoclonal (Ready-to-Use) (EP2) Antibody
Human
IHC-Fr, IHC-P
Unconjugated, Ready-to-Use
3 ml/$427; 7 ml/$606; 15 ml/$1,016
PR / Progesterone Receptor Rabbit anti-Human Polyclonal (pSer190) Antibody
Human, Monkey
ICC, IF, IHC, IHC-P, IP, WB
Unconjugated
30 µl/$263; 100 µl/$315; 200 µl/$379
Viewing 1-25
of 276
product results
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.
