Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Calcineurin A alpha (PPP3CA), a PP2B type serine/threonine phosphatase, is a catalytic subunit of calcineurin which acts as a calcium-dependent and calmodulin-stimulated modifier of phosphorylation status. PPP3CA has been shown to function in calcium signaling and is believed to function in the calmodulin activation of calcineurin, motor neuron disease and neuronal reorganization after ischemic injury.
Western blot of human recombinant Calcineurin A fusion protein using Calcineurin A Antibody, pAb, Rabbit (0. 5 ug/ml). The signal was developed with IRDye 800 Conjugated Goat Anti-Rabbit IgG. Predicted Size: 115 kD. Observed Size: 115 kD.
Western blot of tissue lysates using Calcineurin A Antibody, pAb, Rabbit (0. 5 ug/ml). The signal was developed with IRDye 800 Conjugated Goat Anti-Rabbit IgG. Predicted Size: 59 kD. Observed Size: 60 kD, 32kD.