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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PPP3CA / CCN1 / Calcineurin A Antibody (aa490‑514) LS‑C21072
Antibody
Calcineurin A antibody LS-C21072 is an unconjugated rabbit polyclonal antibody to Calcineurin A (PPP3CA / CCN1) from mouse, rat, bat and other species. Validated for ELISA, IP and WB.
Catalog
Size
Price
LS-C21072-200
200 µg
Unavailable

Popular PPP3CA / CCN1 / Calcineurin A Products

Antibody
Species: Human, Mouse, Rat, Bovine
Applications: IHC, Western blot
Antibody
Species: Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Xenopus
Applications: IHC, Western blot
Anti-PPP3CA / Calcineurin A antibody IHC of human tonsil, lymphocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5673 concentration 5 ug/ml.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Western blot
Antibody
Species: Human, Mouse, Rat, Bovine
Applications: IHC, Western blot
Anti-PPP3CA / CCN1 / Calcineurin A antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10919 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Mouse, Rat, Dog, Rabbit
Applications: IHC, IHC - Paraffin, Western blot, Immunoprecipitation

Product Description

Calcineurin A antibody LS-C21072 is an unconjugated rabbit polyclonal antibody to Calcineurin A (PPP3CA / CCN1) from mouse, rat, bat and other species. Validated for ELISA, IP and WB.
About PPP3CA / CCN1 / Calcineurin A
Calcineurin A alpha (PPP3CA), a PP2B type serine/threonine phosphatase, is a catalytic subunit of calcineurin which acts as a calcium-dependent and calmodulin-stimulated modifier of phosphorylation status. PPP3CA has been shown to function in calcium signaling and is believed to function in the calmodulin activation of calcineurin, motor neuron disease and neuronal reorganization after ischemic injury. Q08209 NM_000944 NP_000935.1

PPP3CA Antibody, Calcineurin A Antibody, CALN Antibody, CALNA Antibody, CALNA1 Antibody, CNA1 Antibody, PPP2B Antibody, Calcineurin A alpha Antibody, CAM-PRP catalytic subunit Antibody, CCN1 Antibody, CNA Antibody, CNA alpha Antibody, pp2b-alpha Antibody


Specifications

Target
Bovine PPP3CA / CCN1 / Calcineurin A
Host
Rabbit
Reactivity
Bovine, Mouse, Rat, Bat, Hamster (tested or 100% immunogen sequence identity)
Predicted
Human, Monkey, Dog, Horse, Xenopus (at least 90% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Ammonium sulfate precipitation
Modifications
Unmodified
Applications
  • Western blot
  • Immunoprecipitation
  • ELISA
  • (applications tested for the base form of this product only)
Immunogen
Synthetic peptide, 25aa, corresponding to aa 490-514 (MPSDANLNSINKALASETNGTDSNG) of bovine Calcineurin/PP2B A, alpha. Percent identity by BLAST analysis: Mouse, Rat, Hamster, Elephant, Panda, Bat, Bovine (100%); Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Dog, Horse (96%); Opossum, Platypus, Xenopus (92%); Turkey, Chicken (84%).
Epitope
aa490-514
Specificity
Recognizes Bovine Calcineurin/PP2B Aa, MW:~58kD. Species cross-reactivity: Human, mouse, rat and rabbit. Species sequence homology: Xenopus 23/25.
Usage
Suitable for use in ELISA and Western Blot. Western Blot: 0.5-2 ug/ul. Detected Calcineurin/PP2B A alpha. in a rat and bovine brain cytosol preparations respectively. Immunoprecipitation: 4 ug. Detected Calcineurin/PP2B A alpha. from 500 ug of rat and bovine brain cytosol preparations.
Presentation
200 ul of 0.1 M Tris-glycine, 0.15 M sodium chloride, 0.05% sodium azide, 30% glycerol.
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/17/2018

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