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Anti-PPP1R13L / iASPP Antibody (aa780-797) LS-C42655

Ordering

Wt. Vol. Conc. Price
50 µg - 1 mg/ml $375
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular PPP1R13L / iASPP Antibodies

Anti-PPP1R13L / iASPP Antibody (aa780-797) IHC-plus™ LS-B408
Rabbit Polyclonal to Human PPP1R13L / iASPP
Human
IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-PPP1R13L / iASPP Antibody (aa75-125) IHC-plus™ LS-B5248
Rabbit Polyclonal (IgG) to Human PPP1R13L / iASPP
Human
IHC - Paraffin, Western blot, Immunoprecipitation
Unconjugated
Immunohistochemistry Image
Anti-PPP1R13L / iASPP Antibody (aa756-805) IHC-plus™ LS-B11881
Rabbit Polyclonal to Human PPP1R13L / iASPP
Human, Mouse, Rat, Dog, Horse, Rabbit
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human PPP1R13L / iASPP
Human
Western blot, ELISA
Unconjugated

Details

Human PPP1R13L / iASPP
Rabbit
Human (tested or 100% immunogen sequence identity)
Mouse, Dog (at least 90% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Purified
Unmodified

Applications

  • Western blot (1:1000 - 1:5000)
  • ELISA (1:40000 - 1:160000)

Specificity and Use

PPP1R13L / iASPP antibody was raised against synthetic peptide corresponding amino acids 780-797 of human iASPP (isoform 1) protein.
aa780-797
Detects human inhibitor of apoptosis stimulating protein of p53 (iASPP), which plays a central role in regulation of apoptosis and transcription via its interaction with NFkB and p53 proteins. At present, the iASPP gene is thought to encode three isoforms; isoform 1 is predominantly located in the cytoplasm, whilst isoforms 2 and 3 are nuclear proteins. iASPP is highly expressed in the heart, placenta and prostate. iASPP has been shown to have oncogenic properties in human breast carcinomas.
Western Blot: LS-C42655 detects a bands of approximately 100 and 50kD corresponding to iASPP isoforms 1 and 2 respectively.

Packaging

PBS, pH 7.2, 0.01% sodium azide.
For research use only.

About PPP1R13L / iASPP

Q8WUF5 NM_006663 NP_006654.2

PPP1R13L Antibody, IASPP Antibody, Inhibitor of ASPP protein Antibody, NFkB-interacting protein 1 Antibody, NKIP1 Antibody, RAI4 Antibody, RAI Antibody, Retinoic acid induced 4 Antibody, NFkB interacting protein 1 Antibody, PPP1R13BL Antibody, Protein iASPP Antibody, RelA-associated inhibitor Antibody, PPP1R13B-like protein Antibody

Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis.

Requested From: United States
Date Requested: 12/9/2016

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