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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PPP1R12A / MYPT1 Antibody (Arg690) LS‑C176432
MYPT1 antibody LS-C176432 is an unconjugated rabbit polyclonal antibody to MYPT1 (PPP1R12A) from human, mouse and rat. Validated for IHC and WB.
Catalog
Size
Price
LS-C176432-100
100 µl
Unavailable

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Product Description

MYPT1 antibody LS-C176432 is an unconjugated rabbit polyclonal antibody to MYPT1 (PPP1R12A) from human, mouse and rat. Validated for IHC and WB.
About PPP1R12A / MYPT1
Myosin phosphatase target subunit 1, which is also called the myosin-binding subunit of myosin phosphatase, is one of the subunits of myosin phosphatase. Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho. The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation, which results in contraction of smooth muscle and interaction of actin and myosin in nonmuscle cells. O14974 NM_002480 NP_002471.1

PPP1R12A Antibody, M130 Antibody, MYPT1 Antibody, MBS Antibody, Myosin binding subunit Antibody


Specifications

Target
Human PPP1R12A / MYPT1
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin
  • Western blot
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic peptide around Arg690 of human MYPT1
Epitope
Arg690
Specificity
Human MYPT1
Presentation
PBS, pH 7.2, 0.05% sodium azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

IHC of MYPT1 (R690) pAb in paraffin-embedded human breast carcinoma tissue.
IHC of MYPT1 (R690) pAb in paraffin-embedded human breast carcinoma tissue.

Western blot

Western blot of MYPT1 (R690) pAb in extracts from COS7 cells.
Western blot of MYPT1 (R690) pAb in extracts from COS7 cells.

Immunohistochemistry

IHC of MYPT1 (R690) pAb in paraffin-embedded human breast carcinoma tissue.
IHC of MYPT1 (R690) pAb in paraffin-embedded human breast carcinoma tissue.

Western blot

Western blot of MYPT1 (R690) pAb in extracts from COS7 cells.
Western blot of MYPT1 (R690) pAb in extracts from COS7 cells.

Immunohistochemistry

IHC of MYPT1 (R690) pAb in paraffin-embedded human breast carcinoma tissue.
IHC of MYPT1 (R690) pAb in paraffin-embedded human breast carcinoma tissue.

Western blot

Western blot of MYPT1 (R690) pAb in extracts from COS7 cells.
Western blot of MYPT1 (R690) pAb in extracts from COS7 cells.

Immunohistochemistry

IHC of MYPT1 (R690) pAb in paraffin-embedded human breast carcinoma tissue.
IHC of MYPT1 (R690) pAb in paraffin-embedded human breast carcinoma tissue.

Western blot

Western blot of MYPT1 (R690) pAb in extracts from COS7 cells.
Western blot of MYPT1 (R690) pAb in extracts from COS7 cells.


Requested From: 
Date Requested: 6/19/2018

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