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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PPP1R12A / MYPT1 Antibody (aa661‑710) LS‑C117671
MYPT1 antibody LS-C117671 is an unconjugated rabbit polyclonal antibody to MYPT1 (PPP1R12A) from human, mouse and rat. Validated for IHC, Peptide-ELISA and WB. Cited in 1 publication.
Catalog
Size
Price
LS-C117671-50
50 µl
Unavailable
LS-C117671-100
100 µl
Unavailable

Popular PPP1R12A / MYPT1 Products

Antibody
Species: Human, Monkey, Mouse, Rat, Dog, Horse, Rabbit, Chicken, Zebrafish
Applications: Western blot
Anti-PPP1R12A / MYPT1 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3836 concentration 3.75 ug/ml.
Species: Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Horse
Applications: IHC, IHC - Paraffin
Antibody
Species: Human, Chicken
Applications: Western blot
IHC of paraffin-embedded human breast carcinoma, using MYPT1 (Phospho-Thr696) Antibody. The sample on the right was incubated with synthetic peptide.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Immunofluorescence, Peptide Enzyme-Linked Immunosorbent Assay
Antibody
Species: Human
Applications: Western blot, Immunoprecipitation

Product Description

MYPT1 antibody LS-C117671 is an unconjugated rabbit polyclonal antibody to MYPT1 (PPP1R12A) from human, mouse and rat. Validated for IHC, Peptide-ELISA and WB. Cited in 1 publication.
About PPP1R12A / MYPT1
Myosin phosphatase target subunit 1, which is also called the myosin-binding subunit of myosin phosphatase, is one of the subunits of myosin phosphatase. Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho. The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation, which results in contraction of smooth muscle and interaction of actin and myosin in nonmuscle cells. O14974 NM_002480 NP_002471.1

PPP1R12A Antibody, M130 Antibody, MYPT1 Antibody, MBS Antibody, Myosin binding subunit Antibody


Specifications

Target
Human PPP1R12A / MYPT1
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC (1:50 - 1:100)
  • Western blot (1:500 - 1:1000)
  • Peptide Enzyme-Linked Immunosorbent Assay (1:1000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Failed Applications
  • IHC - Paraffin
Immunogen
Synthetic peptide from human MYPT1 (aa661-710).
Epitope
aa661-710
Specificity
MYPT1 (Ab-696) Antibody detects endogenous levels of total MYPT1 protein.
Presentation
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Storage
Store at -20°C for up to 1 year.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

Publications (1)

1
Constitutive Phosphorylation of Cardiac Myosin Regulatory Light Chain in vivo. Battiprolu PK, Cowley PM, Chen G, Gerard RD, Pinto JR, Hill JA, Baker AJ, Kamm KE, Stull JT. The Journal of biological chemistry. Mar; [Full Text Article] [PubMed:25733667]

Customer Reviews (0)


Images


Western blot

Western blot of extracts from COS7 cells, using MYPT1 (Ab-696) Antibody. The lane on the right is treated with the synthesized peptide.
Western blot of extracts from COS7 cells, using MYPT1 (Ab-696) Antibody. The lane on the right is treated with the synthesized peptide.

Western blot

Western blot of extracts from COS7 cells, using MYPT1 (Ab-696) Antibody. The lane on the right is treated with the synthesized peptide.
Western blot of extracts from COS7 cells, using MYPT1 (Ab-696) Antibody. The lane on the right is treated with the synthesized peptide.

Western blot

Western blot of extracts from COS7 cells, using MYPT1 (Ab-696) Antibody. The lane on the right is treated with the synthesized peptide.
Western blot of extracts from COS7 cells, using MYPT1 (Ab-696) Antibody. The lane on the right is treated with the synthesized peptide.

Western blot

Western blot of extracts from COS7 cells, using MYPT1 (Ab-696) Antibody. The lane on the right is treated with the synthesized peptide.
Western blot of extracts from COS7 cells, using MYPT1 (Ab-696) Antibody. The lane on the right is treated with the synthesized peptide.


Requested From: 
Date Requested: 6/24/2018

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