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Human PPOX | |
Rabbit | |
Human, Monkey, Mouse, Rat, Bovine, Horse, Pig, Rabbit (tested or 100% immunogen sequence identity) | |
Bat, Dog, Hamster (at least 90% immunogen sequence identity) | |
Polyclonal | |
Unconjugated. Also available conjugated with Biotin, FITC, HRP. | |
Immunoaffinity purified | |
Unmodified |
PPOX antibody was raised against synthetic peptide located between aa35-84 of human PPOX (P50336, NP_000300). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Panda, Bovine, Rabbit, Horse, Pig (100%); Hamster, Elephant, Dog, Bat, Opossum (92%); Salmon, Stickleback (91%); Guinea pig (85%). | ||
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aa35-84 | ||
Human PPOX | ||
Western Blot: Suggested dilution at 1 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody. |
Lyophilized from PBS with 2% sucrose | |
Distilled water | |
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles. | |
For research use only. |
PPOX Antibody, PPO Antibody, Protoporphyrinogen oxidase Antibody, V290M Antibody, Variegate porphyria Antibody, VP Antibody
PPOX is the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified.
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