Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Ammonium sulfate precipitation
Western blot (5 - 10 µg/ml)
Specificity and Use
PPM1G antibody was raised against synthetic peptide corresponding to aa311-323 (NH2-Thr-Pro-Pro-Arg-Gly-Met-Ile-Thr-Lys-Gln-Ala-Lys-Lys-COOH) of the C-terminal of human PP1 gamma 1 catalytic subunit (MW 37kD) (KLH coupled).
Recognizes Protein Phosphatase 1 gamma 1 (Ser, Thr) (PP1g1). Does not cross-react with other recombinant PP1 isoforms. Species cross-reactivity: Human, mouse, rat and bovine.
Suitable for use in Western Blot and Immunoprecipitation. Western Blot: 5-10 ug/ml.
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression.