PPID / Cyclophilin D

peptidylprolyl isomerase D

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Proposed to act as a co-chaperone in HSP90 complexes such as in unligated steroid receptors heterocomplexes. Different co-chaperones seem to compete for association with HSP90 thus establishing distinct HSP90-co-chaperone-receptor complexes with the potential to exert tissue-specific receptor activity control. May have a preference for estrogen receptor complexes and is not found in glucocorticoid receptor complexes. May be involved in cytoplasmic dynein-dependent movement of the receptor from the cytoplasm to the nucleus. May regulate MYB by inhibiting its DNA-binding activity. Involved in regulation of AHR signaling by promoting the formation of the AHR:ARNT dimer; the function is independent of HSP90 but requires the chaperone activity. Involved in regulation of UV radiation-induced apoptosis. Promotes cell viability in anaplastic lymphoma kinase-positive anaplastic large-cell lymphoma (ALK+ ALCL) cell lines. May be involved in hepatitis C virus (HCV) replication and release.

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Products

Antibodies (62)

ELISA Kits (12)

Proteins (10)

Type

Development Kit (3)

Over-Expression Lysate (2)

Primary (62)

Recombinant (8)

Sandwich (9)

Target

PPID / Cyclophilin D (84)

Reactivity

Human (65)

Mouse (43)

Rat (41)

Bat (6)

Bovine (6)

Chicken (4)

Chimpanzee (6)

Dog (3)

Gibbon (6)

Guinea pig (4)

Hamster (1)

Horse (6)

Monkey (10)

Pig (6)

Porcine (1)

Rabbit (8)

Xenopus (3)

Zebrafish (7)

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Application

IHC (13)

IHC-P (13)

WB (58)

Flo (6)

ELISA (9)

ICC (5)

IF (6)

IP (6)

Peptide-ELISA (2)

Host

rabbit (57)

mouse (4)

goat (1)

Product Group

DevKit DuoPlus (3)

IHCPlus (2)

Isotype

Ig (1)

IgG (25)

IgG1 (1)

IgG2a,k (1)

IgG2b,k (1)

Clonality

monoclonal mc (3)

polyclonal pc (59)

Clone

4C7 (1)

AT1B8 (1)

Format

96-Well Strip Plate (9)

Antibody Pair and Standard (3)

APC (3)

APC Conjugated (4)

Biotin Conjugated (6)

Cy3 Conjugated (3)

Cy7 Conjugated (3)

DY488 Conjugated (1)

DY550 Conjugated (1)

FITC Conjugated (6)

HRP Conjugated (6)

PE Conjugated (4)

Unconjugated (28)

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Epitope

aa7-191 (8)

aa7-206 (8)

aa9-189 (8)

aa179-228 (4)

aa71-120 (4)

aa161-370 (2)

321-370 aa, C-terminal (1)

aa105-116 (1)

aa175-225 (1)

aa320-370 (1)

aa351-370 (1)

aa85-115 (1)

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Publications

No (84)

Sample Type

Cell Culture Supernatants (5)

Cell Lysates (5)

Plasma (4)

Serum (4)

Tissue Homogenates (5)

Tag

6His, N-terminus + 6His, C-terminus (2)

GST (1)

His (1)

His-T7 (3)

Myc-DDK (Flag) (3)

Species

Human (7)

Mouse (1)

Rat (1)

Source

293T Cells (1)

E. coli (6)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (3)

Biologically Active

Biologically active (1)

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IHC-plus™ PPID / Cyclophilin D Antibody (clone 4C7) LS-B10440

(4.0) Rating

Antibody:

PPID / Cyclophilin D Mouse anti-Human Monoclonal (4C7) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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PPID / Cyclophilin D Antibody (aa71-120) LS-B5870

Antibody:

PPID / Cyclophilin D Rabbit anti-Human Polyclonal (aa71-120) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

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PPID / Cyclophilin D Antibody (aa71-120, HRP) LS-C462096

Antibody:

PPID / Cyclophilin D Rabbit anti-Human Polyclonal (aa71-120) (HRP) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Pig, Horse, Bat, Rat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

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PPID / Cyclophilin D Antibody (aa71-120, Biotin) LS-C462094

Antibody:

PPID / Cyclophilin D Rabbit anti-Human Polyclonal (aa71-120) (Biotin) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Pig, Horse, Bat, Rat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

PPID / Cyclophilin D Antibody (aa71-120, FITC) LS-C462095

Antibody:

PPID / Cyclophilin D Rabbit anti-Human Polyclonal (aa71-120) (FITC) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Pig, Horse, Bat, Rat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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Rat PPID / Cyclophilin D Protein (Recombinant His-T7) (aa7-191) - LS-G13952

Source:

E. coli

Tag:

His-T7

Molecular Weight:

24.0 kDa

Price:

10 µg/$291; 50 µg/$502; 100 µg/$802; 200 µg/$1,002; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334

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PPID / Cyclophilin D Antibody (aa7-206) LS-C293604

Antibody:

PPID / Cyclophilin D Rabbit anti-Human Polyclonal (aa7-206) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IP, WB

Format:

Unconjugated

Price:

100 µl/$303; 200 µl/$343; 500 µl/$476; 1 ml/$543; 2 ml/$715; 5 ml/$1,182

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PPID / Cyclophilin D Antibody LS-C756658

Antibody:

PPID / Cyclophilin D Mouse anti-Human Monoclonal Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

Flo, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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PPID / Cyclophilin D Antibody LS-C662589

Antibody:

PPID / Cyclophilin D Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ICC, IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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PPID / Cyclophilin D Antibody LS-C757482

Antibody:

PPID / Cyclophilin D Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IF, IHC-P, WB

Format:

Unconjugated

Price:

200 µl/$393

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PPID / Cyclophilin D Antibody (aa179-228) LS-C111939

Antibody:

PPID / Cyclophilin D Rabbit anti-Human Polyclonal (aa179-228) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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PPID / Cyclophilin D Antibody (aa85-115) LS-C163901

Antibody:

PPID / Cyclophilin D Rabbit anti-Human Polyclonal (aa85-115) Antibody

Reactivity:

Mouse, Human

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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PPID / Cyclophilin D Antibody LS-C755190

Antibody:

PPID / Cyclophilin D Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

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PPID / Cyclophilin D Antibody (aa161-370) LS-C376388

Antibody:

PPID / Cyclophilin D Rabbit anti-Human Polyclonal (aa161-370) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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Human PPID / Cyclophilin D (Sandwich ELISA) ELISA Kit - LS-F40231

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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PPID / Cyclophilin D Antibody LS-C765930

Antibody:

PPID / Cyclophilin D Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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PPID / Cyclophilin D Antibody LS-C346382

Antibody:

PPID / Cyclophilin D Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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PPID / Cyclophilin D Antibody LS-C667660

Antibody:

PPID / Cyclophilin D Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ICC, IF, WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321

Select

PPID / Cyclophilin D Antibody (aa161-370) LS-C376385

Antibody:

PPID / Cyclophilin D Rabbit anti-Human Polyclonal (aa161-370) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

Select

PPID / Cyclophilin D Antibody (aa351-370) LS-C312630

Antibody:

PPID / Cyclophilin D Rabbit anti-Human Polyclonal (aa351-370) Antibody

Reactivity:

Rabbit, Guinea pig, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

Select

PPID / Cyclophilin D Antibody (clone AT1B8) LS-C755546

Antibody:

PPID / Cyclophilin D Mouse anti-Human Monoclonal (AT1B8) Antibody

Reactivity:

Human

Applications:

ELISA, ICC, WB

Format:

Unconjugated

Price:

50 µl/$303; 100 µl/$365

Select

PPID / Cyclophilin D Antibody (aa7-191) LS-C293606

Antibody:

PPID / Cyclophilin D Rabbit anti-Rat Polyclonal (aa7-191) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IP, WB

Format:

Unconjugated

Price:

100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261

Select

PPID / Cyclophilin D Antibody LS-C817020

Antibody:

PPID / Cyclophilin D Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC-P, IP, WB

Format:

Unconjugated

Price:

100 µl/$412

Select

PPID / Cyclophilin D Antibody (321-370 aa, C-terminal) LS-C386900

Antibody:

PPID / Cyclophilin D Rabbit anti-Human Polyclonal (321-370 aa, C-terminal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

PPID / Cyclophilin D Antibody LS-C742848

Antibody:

PPID / Cyclophilin D Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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